Effect of the opioid remifentanil on cellular immune response in the rat

International Immunopharmacology

Volumn 1, Issue 4, 2001, Pages 713-719

  Sacerdote, P ^a   Gaspani, L ^a   Rossoni, G ^a   Panerai, A E ^a   Bianchi, M ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Fentanyl; Lymphoproliferation; NK activity; Opioid induced immunosuppression

Indexed keywords

FENTANYL; OPIATE; REMIFENTANIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG ELIMINATION; DRUG HALF LIFE; IMMUNE DEFICIENCY; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; MALE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN; SPLEEN CELL;

ANALGESICS, OPIOID; ANIMALS; IMMUNOSUPPRESSIVE AGENTS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MALE; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035103115     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(01)00005-4     Document Type: Article

References (24)

1. Mechanism of morphine-induced immunomodulation
2. Opioid modulation of immune responses: Effects on phagocyte and lymphoid cell populations
3. Effects of tramadol on immune responses and nociceptive thresholds in mice
4. Antinociceptive and immunosuppressive effects of opiate drugs: A structure-related activity study
5. Opiates and infections
6. Effect of morphine on growth of metastatic colon cancer in vivo
7. Perioperative immunomodulation in cancer surgery
8. Impaired humoral immunity is associated with development of methicillin-resistent Staphylococcus aureus infections after esophageal surgery
9. Molecular response to surgical stress
10. Effects of anesthesia based on large versus small doses of fentanyl on natural killer cell cytotoxicity in the perioperative period
11. Evaluation of NK and LAK cell activities in neoplastic patients during treatment with morphine
12. Morphine inhibits spontaneous and cytokine enhanced natural killer cell cytotoxicity in volunteers
13. An overview of remifentanil
14. Optimizing whole blood lymphocyte proliferation in the rat
15. Evidence for an opioid inhibitory effect on T cell proliferation
16. Design, synthesis and pharmacological evaluation of ultra-short to long acting opioid analgesics
17. Early nociceptive events influence the temporal profile, but not the magnitudine, of the tonic response to subcutaneous formalin: Effects with remifentanil
18. Morphine-induced modulation of immune status: Evidence for opioid receptor mediation and compartment specificity
19. Involvement of brain opiate receptors in the immune-suppressive effect of morphine
20. The periaqueductal gray matter mediates opiate-induced immunosuppression
21. The relevance of opioid receptors on immunocompetence and immune homeostasis
22. Evidence for central opioid receptors in the immunomodulatory effects of morphine; review of potential mechanism(s) of action
23. Opioid mediated effects on the immune system: Sympathetic immune system involvement
24. Effects of tramadol and morphine on immune responses and pain after surgery in cancer patients