Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: Implications for basic and clinical research

Leukemia

Volumn 15, Issue 2, 2001, Pages 286-288

  Reichel, M ^a   Gillert, E ^a   Breitenlohner, I ^a   Angermuller S ^a   Fey, G H ^a   Marschalek, R ^a   Repp, R ^a   Greil, J ^a   Beck, J D ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; COMPLEMENTARY DNA; DNA; DNA FRAGMENT; MESSENGER RNA; OLIGONUCLEOTIDE; RNA; TUMOR MARKER;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 4; CLINICAL RESEARCH; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA DAMAGE; DNA DETERMINATION; DNA REPAIR; GENE AMPLIFICATION; GENE TRANSLOCATION; GENETIC ANALYSIS; HUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0035101959     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402018     Document Type: Article

References (14)

1. Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias
2. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF4 gene
3. Involvement of a homolog of Drosophila-trithorax by 11q23 chromosomal translocations in acute leukemias
4. A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level
5. The exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukemias
6. The structure of the human ALL-1/MLL/HRX gene
7. The exon/intron structure of the human AF4 gene, a member of the AF4/LAF4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute Leukemia
8. Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia
9. Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11)
10. Rapid isolation of chromosomal breakpoints from patient with t(4;11) acute lymphoblastic leukemia: Implications for basic and clinical research
11. A DNA damage repair mechanism in involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells
12. Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): The damage-repair model of translocation
13. Backtracking leukemia to birth: Identification of clonotypic gene fusion sequences in neonatal blood spots
14. Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood ALL