Microgravimetric DNA sensor based on quartz crystal microbalance: Comparison of oligonucleotide immobilization methods and the application in genetic diagnosis

Biosensors and Bioelectronics

Volumn 16, Issue 1-2, 2001, Pages 85-95

  Zhou, Xi Chun ^a   Huang, Li Qun ^b   Li, Sam Fong Yau ^b  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

thalassaemia; Biosensor; DNA hybridization; Monolayer; Multilayer; Quartz crystal microbalance

Indexed keywords

AVIDIN; BIOTIN; BUFFER; OLIGONUCLEOTIDE; SILICON DIOXIDE;

ADSORPTION; AMINO ACID SEQUENCE; ARTICLE; BETA THALASSEMIA; BIOSENSOR; CONCENTRATION (PARAMETERS); COVALENT BOND; DNA HYBRIDIZATION; DNA PROBE; FILM; GENETIC DISORDER; GRAVIMETRY; INTERMETHOD COMPARISON; IONIC STRENGTH; PRODUCTIVITY; PROTEIN IMMOBILIZATION; PROTEIN PROTEIN INTERACTION;

BIOSENSING TECHNIQUES; DNA PROBES; HUMANS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDES; QUARTZ;

EID: 0035101797     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0956-5663(00)00136-6     Document Type: Article

References (35)

1. Amplified microgravimetric quartz-crystal-microbalance analysis of oligonucleotide complexes: A route to a Tay-Sachs sensor
2. Assembly of alternating polyelectrolyte and protein multilayer films for immunosensing
3. Quartz crystal microbalance study of DNA immobilization and hybridization for nucleic acid sensor development
4. Buildup of ultrathin multilayer films by a self-assembly process 3. Consecutively alternating adsorption of anionic and cationic polyelectrolytes on charged surfaces
5. Prospects for nucleic-acid biosensors
6. Insitu surface-detecting technique by using a quartz-crystal microbalance - Interaction behaviors of proteins onto a phospholipid monolayer at the air-water-interface
7. Study of protein-DNA interactions by surface-plasmon resonance (real-time kinetics)
8. The physical description of films coating quartz resonators
9. Direct measurement of the adsorption-kinetics of alkanethiolate self-assembled monolayers on a microcrystalline gold surface
10. Assembly of thin-films by means of successive deposition of alternate layers of DNA and poly(allylamine)
11. Assembly of multicomponent protein films by means of electrostatic layer-by-layer adsorption
12. Spectroscopic study of thin multilayer films of the complexes of nucleic acids with cationic amphiphiles and polycations: Their possible use as sensor elements
13. Behavior of piezoelectric quartz crystals in solutions with application to the determination of iodide
14. Direct monitoring of DNA polymerase reaction on a quartz crystal microbalance
15. Quartz crystal microbalance sensor deposited with LB films of conducting polymers and application to heavy metal ions analysis
16. Kinetic studies of sequence-specific binding of GCN4-bZIP peptide to DNA strands immobilized on 27-MHz quartz crystal microbalance
17. New trends in electrochemical analysis of nucleic acids
18. Oligonucleotide hybridization observed by surface-plasmon optical techniques
19. Verwendung von schwingquarzen zur wägung dunner schichten und zur mikrowägung
20. Kinetic of hybridization of interfacial RNA homopolymers studies by thickness-shear mode acoustic wave sensor
21. Kinetic of interfacial nucleic acid hybridization studied by acoustic network analysis
22. Optical properties and the structure of Langmuir-Blodget films of the complexes of nucleic acids with lipids and synthetic amphiphilic molecules 2. IR spectra, hydration and conformational state of DNA in a multilayer
23. Multilayer films containing immobilized nucleic acids. Their structure and possibilities in biosensor applications
24. Molecular characterization of beta-thalassemia in Singaporean Chinese-application to prenatal-diagnosis
25. The amplification refractory mutation system (ARMS) - A rapid and direct prenatal diagnostic-technique for beta-thalassemia in Singapore
26. Molecular heterogeneity of β-thalassaemia in Malaysia: A practical approach to diagnosis
27. Adsorption, immobilization, and hybridization of DNA studied by the use of quartz-crystal oscillators
28. Immobilization of DNA on silver surface of bulk acoustic wave sensor and its application to the study of UV-damage
29. Detection of organic amines in liquid with chemically coated quartz crystal microbalance
30. Organic vapor sensors based on quartz crystal microbalance with self-assembled monolayers
31. Amplified microgravimetric gene sensor using Au nanoparticle modified oligonucleotide