The D3R partial agonist, BP 897, attenuates the discriminative stimulus effects of cocaine and D-amphetamine and is not self-administered

Behavioural Pharmacology

Volumn 12, Issue 1, 2001, Pages 1-11

  Beardsley, P M ^a   Sokoloff, P ^a   Balster, R L ^a   Schwartz, J C ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BP 897; Cocaine; D amphetamine; Drug discrimination; Mouse; Rhesus monkey; Self administration

Indexed keywords

BP 4 897; BP 897; COCAINE; DEXAMPHETAMINE; DO 897; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR STIMULATING AGENT; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; DRUG SELF ADMINISTRATION; MALE; MOUSE; NONHUMAN; RHESUS MONKEY;

EID: 0035096775     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-200102000-00001     Document Type: Article

References (36)

1. Assessment of cocaine-like discriminative stimulus effects of dopamine D3 receptor ligands
2. Self-administration of barbiturates and benzodiazepines: A review
3. Assessment of the discriminative stimulus effects of the D3 dopamine antagonist PNU-99194A in rats: Comparison with psychomotor stimulants
4. Drug abuse potential evaluation in animals
5. Review of self-administration
6. Is there a role for dopamine D3R agents in drug abuse?
7. The self-administration of MK-801 can depend upon drug-reinforcement history and its discriminative stimulus properties are phencyclidine-like in rhesus monkeys
8. The D3R partial agonist, DO897, reduces cocaine self-administration and stimulant discriminative effects but lacks stimulant activity
9. Modulation of cocaine self-administration in the rat through D-3 dopamine receptors
10. D3 receptor test in vitro predicts decreased cocaine self-administration in rats
11. Dopamine D1 and D2 mediation of the discriminative stimulus properties of D-amphetamine and cocaine
12. The role of dopamine receptor subtypes in the discriminative stimulus effects of amphetamine and cocaine in rats
13. Analysis of D2 and D3 receptor-selective ligands in rats trained to discriminate cocaine from saline
14. Opioids: Similarly between evaluations of subjective effects and animal self-administration results
15. A summary of results of a drug self-administration study using substitution procedures in rhesus monkeys
16. Effects of D3-preferring agonists 7-OH-PIPAT and PD-128,907 on motor behaviors and place conditioning
17. Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys
18. Cocaine addiction therapy - Are we partially there?
19. Self-administration of the dopamine D3 agonist 7-OH-DPAT in rhesus monkeys is modified by prior cocaine exposure
20. Molecular mechanisms of drug addiction
21. Common biochemical mechanisms underlying opiate and cocaine addiction
22. Neurochemical evidence that postsynaptic nucleus accumbens D3 receptor stimulation enhances cocaine reinforcement
23. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist
24. Subjective and discriminative effects of drugs
25. Antagonism of cocaine self-administration by the preferential dopamine autoreceptor antagonist, (+)-AJ 76
26. Drug-drug discrimination: Stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum
27. Relationship between the discriminative stimulus properties and subjective effects of drugs
28. Multiple dopamine receptors: The D3 receptor and actions of substances of abuse
29. Dopamine D2/D3 receptors modulate cocaine's reinforcing and discriminative stimulus effects in rhesus monkeys
30. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
31. Dopamine D3 receptor agonists partially reproduce the discriminative stimulus effects of cocaine in squirrel monkeys
32. Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities
33. Discriminative stimulus properties of cocaine in the rat using a two-choice discrete-trial avoidance paradigm