Pictures in molecular medicine hair cell function - It's all a matter of organization

Trends in Molecular Medicine

Volumn 7, Issue 3, 2001, Pages 138-

  Holme, Ralph H ^a   Steel, Karen P ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; INTEGRIN; MYOSIN;

ANIMAL CELL; COCHLEA; CORTI ORGAN; FUNCTIONAL ANATOMY; GENE MUTATION; HAIR CELL; HEARING IMPAIRMENT; MOUSE; NONHUMAN; SHORT SURVEY; STEREOCILIUM; USHER SYNDROME; ANIMAL; DISEASE MODEL; GENETICS; HEARING; METABOLISM; MUTATION; PATHOPHYSIOLOGY; PERCEPTION DEAFNESS; PHYSIOLOGY; REVIEW; SYNDROME; ULTRASTRUCTURE;

ANIMALIA;

ANIMALS; CADHERINS; DISEASE MODELS, ANIMAL; HAIR CELLS, INNER; HEARING; HEARING LOSS, SENSORINEURAL; MICE; MUTATION; SYNDROME;

EID: 0035093670     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(01)01932-3     Document Type: Short Survey

References (8)

1. How the ear's works work
2. Genes involved in deafness
3. Mutations in cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1D
4. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23
5. Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D
6. Stereocilia defects in the sensory hair ceils of the inner ear in mice deficient in integrin α8β1
7. The deafjerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins
8. The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene