Interactions between human osteoarthritic chondrocytes and synovial fibroblasts in co-culture

Clinical and Experimental Rheumatology

Volumn 19, Issue 1, 2001, Pages 27-33

  Huch, K ^a   Stove J ^a   Gunther K P ^a   Puhl, W ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

Chondrocyte; Co culture; Interleukin 1 ; Synovial fibroblast

Indexed keywords

ALGINIC ACID; DNA; INTERLEUKIN 1BETA; METHYLENE BLUE; PROSTAGLANDIN E2; PROTEOGLYCAN; SULFUR 35;

ARTICLE; ASSAY; CARTILAGE CELL; CELL INTERACTION; CELL PROLIFERATION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DNA CONTENT; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FIBROBLAST CULTURE; FLUOROMETRY; HUMAN; HUMAN CELL; IN VIVO STUDY; JOINT; MEASUREMENT; MEDIATOR; MONOLAYER CULTURE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEOGLYCAN SYNTHESIS; SIMULATION; SYNOVIUM;

AGED; CELL COMMUNICATION; CHONDROCYTES; COCULTURE TECHNIQUES; DINOPROSTONE; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; HUMANS; INTERLEUKIN-1; MIDDLE AGED; OSTEOARTHRITIS; PROTEOGLYCANS; SYNOVIAL FLUID;

EID: 0035093590     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Morphometric comparison of synovium from patients with osteoarthritis and rheumatoid arthritis
2. The synovial membrane in osteoarthritis: A histological study including the characterization of the cellular infiltrate present in inflammatory osteoarthritis using monoclonal antibodies
3. Cartilage matrix depletion by rheumatoid synovial cells in tissue culture
4. The effect of synovial tissue on the breakdown of articular cartilage in organ culture
5. A tissue-culture model of cartilage breakdown in rheumatoid arthritis
6. Effect of homologous synovial membrane on adult human articular cartilage in organ culture and failure to influence it with D-penicillamine
7. Matrix depletion of young and old human articular cartilage by cultured autologous synovium fragments: A chondrocyte-independent effect
8. Destruction of articular cartilage by arthritic synovium in vitro: Mechanism of breakdown and effect of indomethacin and prednisolone
9. Tripeptide RGD-dependent adhesion of articular chondrocytes to synovial fibroblasts
10. Intercellular calcium signaling between chondrocytes and synovial cells in co-culture
11. Radiological assessment of osteoarthritis
12. Synthesis and turnover of proteoglycans by human and bovine adult articular chondrocytes cultured in alginate beads
13. A new method for three-dimensional in vitro growth of human cancer cells
14. Culture and growth characteristics of chondrocytes encapsulated in alginate beads
15. Fluorometric assay of DNA in cartilage explants using Hoechst 33258
16. 35S-labeled proteoglycans complexed to alcian blue by rapid filtration in multiwell plates
17. Microdetermination of proteoglycans and glycosaminoglycans in the presence of guanidine hydrochloride
18. Cytokine inter-relationships and their association with disease activity in arthritis
19. Cytokines in synovial fluid. I. The presence of biologically active and immunoreactive IL-1. 1
20. Determination of cytokines in synovial fluids: Correlation with diagnosis and histomorphological characteristics of synovial tissue
21. Concentration of interleukin-1β in serum and synovial fluid in patients with rheumatoid arthritis and those with osteoarthritis
22. Praktische Bedeutung der Zytokinbestimmung im Gelenkpunktat von Patienten mit Arthrosen oder rheumatischen Arthritiden
23. Markers of cartilage and synovial metabolism in joint fluid and serum of patients with chondromalacia of the patella
24. Metalloprotease activity, phospholipase A2 activity and cytokine concentration in osteoarthritis synovial fluids
25. Synovial fluid concentration of five different cytokines in rheumatic disease
26. Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads
27. Dedifferentiated chondrocytes cultured in alginate beads: Restoration of the dedifferentiated phenotype and of the metabolic responses to interleukin-1 β
28. Susceptibility of normal and arthritic human articular cartilage to degradative stimuli
29. Cytokines and focal loss of cartilage in osteoarthritis
30. The synovial activation of chondrocytes: Evidence for complex cytokine interactions involving a possible novel factor
31. Stimulation of human chondrocyte prostaglandin E2 production by recombinant human interleukin-1 and tumor necrosis factor
32. In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases
33. 2 release from cartilage in organ culture
34. Differential effects of interleukin-1α and β on the acid cascade in human synovial cells and chondrocytes in culture
35. Regulation of cartilage oligomeric matrix protein synthesis in human synovial cells and articular chondrocytes
36. Characterization of proteins from human synovium and mononuclear leukocytes that induce resorption of cartilage proteoglycan in vitro
37. Osteoarthritic synovial fluid and synovium supernatants up-regulate tumor necrosis factor receptors on human articular chondrocytes