Miscoding and misincorporation of 8-oxo-guanine during leading and lagging strand synthesis in Escherichia coli

Molecular and General Genetics

Volumn 264, Issue 6, 2001, Pages 836-841

  Watanabe, T ^a   Van Geldorp, G ^a   Najrana, T ^a   Yamamura, E ^a   Nunoshiba, T ^a   Yamamoto, K ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

8 OxodGTP; 8 OxoG; DNA replication; Lagging strand; Leading strand

Indexed keywords

8 HYDROXYGUANINE; BACTERIAL PROTEIN; BACTERIAL PROTEIN SUPF; UNCLASSIFIED DRUG;

ARTICLE; DNA REPLICATION; DNA STRAND; DNA SYNTHESIS; ESCHERICHIA COLI; MUTAGENESIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

BASE SEQUENCE; DNA GLYCOSYLASES; DNA REPLICATION; DNA, BACTERIAL; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FRAMESHIFT MUTATION; GENES, SUPPRESSOR; GUANINE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; N-GLYCOSYL HYDROLASES; RNA, TRANSFER; SEQUENCE DELETION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0035091813     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380000373     Document Type: Article

References (32)

1. Construction of Escherichia coli K12 phr deletion and insertion mutants by gene replacement
2. Escherichia coli mutY gene encodes an adenine glycosylase active on G-A mispairs
3. Effect of single DNA lesions on in vitro replication with DNA polymerase III holoenzyme. Comparison with other polymerases
4. Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization
5. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions
6. Oxidative damage to DNA in mammalian chromatin
7. Unequal fidelity of leading strand and lagging strand DNA replication on the Escherichia coli chromosome
8. Promotion of evolution: Disparity in the frequency of strand-specific misreading between the lagging and leading DNA strands enhances disproportionate accumulation of mutations
9. Mutagenesis by 8-oxoguanine: An enemy within
10. Preferential replication-dependent mutagenesis in the lagging DNA strand in Escherichia coli
11. Adenosine 5′-O-(3-thiotriphosphate) can support the formation of an initiation complex between the DNA polymerase III holoenzyme and primed DNA
12. DNA polymerase III holoenzyme: Structure and function of a chromosomal replicating machine
13. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
14. Prokaryotic DNA replication
15. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
16. Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA
17. A repair system for 8-oxo-7,8-dihydrodeoxyguanine
18. An improved system for selection of forward mutations in an Escherichia coli supF gene carried by plasmids
19. An Escherichia coli plasmid-based, mutational system in which supF mutants are selectable: Insertion elements dominate the spontaneous spectra
20. DNA sequencing with chain-terminating inhibitors
21. A shuttle vector plasmid for studying carcinogen-induced poin mutations in mammalian cells
22. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
23. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter
24. Functional cooperation of MutT, MutM and MutY proteins in preventing mutations caused by spontaneous oxidation of guanine nucleotide in Escherichia coli
25. 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity
26. Greater susceptibility to mutations in lagging strand of DNA replication in Escherichia coli than in leading strand
27. Leading versus lagging strand mutagenesis induced by 7,8-dihydro-8-oxo-2′-deoxyguanosine in Escherichia coli
28. Mechanistic studies of ionizing radiation and oxidative mutagenesis: Genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome
29. Enzymatic repair mechanisms for base modifications induced by oxygen radicals
30. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors
31. The unusual mutagenic specificity of an E. coli mutator gene