Reduction of functional N-methyl-D-aspartate receptors in neurons by RNase P-mediated cleavage of the NR1 mRNA

Journal of Neurochemistry

Volumn 76, Issue 5, 2001, Pages 1386-1394

  Yen, Laising ^a   Gonzalez Zulueta, Mirella ^b   Feldman, Alicia ^c   Yuan, Yan ^b   Fryer, Hugh ^b   Dawson, Ted ^a   Dawson, Valina ^a   Kalb, Robert G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Catalytic RNA; Excitotoxicity; Glutamate receptor; Ribozyme

Indexed keywords

ENDONUCLEASE; EXCITOTOXIN; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT; RIBONUCLEASE; RIBOZYME;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOTOXICITY; DNA FLANKING REGION; EMBRYO; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; RECEPTOR AFFINITY; RNA BINDING; RNA SEQUENCE;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CEREBRAL CORTEX; EMBRYO; ENDORIBONUCLEASES; GENETIC VECTORS; MOLECULAR SEQUENCE DATA; N-METHYLASPARTATE; NEURONS; OLIGODEOXYRIBONUCLEOTIDES; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RIBONUCLEASE P; RIBONUCLEASE T1; RNA EDITING; RNA, CATALYTIC; RNA, GUIDE; RNA, MESSENGER; SIMPLEXVIRUS;

ANIMALIA; HERPES; SIMPLEXVIRUS;

EID: 0035091786     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00153.x     Document Type: Article

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