Topology of the signal transduction of the G protein-coupled somatostatin receptor sst2 in human glioma cells

Cell and Tissue Research

Volumn 303, Issue 1, 2001, Pages 27-34

  Mentlein, Rolf ^a   Held Feindt, Janka ^a   Krisch, Brigitte ^a  

^a Kiel and Lungen Clinic Grosshansdorf   (Germany)

Author keywords

Caveolae; Density shift gradient centrifugation; G proteins; Immunoelectron microscopy; Immunogold labeling; Internalization; Somatostatin receptor

Indexed keywords

CAVEOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; SOMATOSTATIN RECEPTOR;

ARTICLE; CELL VACUOLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; INTERNALIZATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES; CAVEOLIN 1; CAVEOLINS; ENDOCYTOSIS; GLIOBLASTOMA; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HORMONES; HUMANS; MICROSCOPY, IMMUNOELECTRON; OCTREOTIDE; ORGANELLES; RABBITS; RECEPTORS, SOMATOSTATIN; SIGNAL TRANSDUCTION; SOMATOSTATIN; TUMOR CELLS, CULTURED;

EID: 0035089332     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410000302     Document Type: Article

References (28)

1. Caveolae: Where incoming and outgoing messengers meet
2. The subcellular localisation of the G-protein Giα in the basal ganglia reveals its potential role in both signal transduction and vesicle trafficking
3. Isolation and preliminary characterization of the major membrane boundaries of endocytic pathways in lymphocytes
4. Identification of caveolin and caveolin-related proteins in the brain
5. Signal transduction of a G protein-coupled receptor in caveolae: Co-localization of endothelin and its receptor with caveolin
6. Differential distribution of alpha subunits and beta gamma subunits of heterotrimeric G proteins on Golgi membranes of the exocrine pancreas
7. Expression of somatostatin receptor subtypes in cultured astrocytes and gliomas
8. Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding
9. 2) in human glioma cells
10. Somatostatin receptors in gliomas
11. 2A somatostatin receptor
12. The size of sites containing SR proteins in human nuclei: Problems associated with characterizing small structures by immunogold labelling
13. Affinity-purification and characterization of caveolins from the brain: Differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types
14. Somatostatin receptors in Neuro2A neuroblastoma cells: Ligand internalisation
15. Agonist-mediated endocytosis of somatostatin receptor subtype 3 involves beta-arrestin und clathrin-coated vesicles
16. Immunoelectronmicroscopic analysis of the ligand-induced internalisation of the somatostatin receptor subtype 2 in cultured human glioma cells
17. Membrane microdomains and caveolae
18. Organized endothelial cell surface signal transduction in caveolae distinct from glycosylphosphatidylinositol-anchored protein microdomains
19. Endocytosis and molecular sorting
20. The elucidation of somatostatin receptor functions: A current view
21. Localisation of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane
22. 2 receptor subtypes: A confocal-microscopic study using novel fluorescent somatostatin derivatives
23. Caveolae and caveolins
24. Molecular pharmacology of somatostatin receptor subtypes
25. Dual pathways of internalisation of the cholecystokinin receptor
26. Distinct agonist-mediated endocytosis of cloned rat somatostatin receptor subtypes expressed in insulinoma cells
27. Requirement of caveolae microdomains in extracellular signal-regulated kinase and focal adhesion kinase activation induced by endothelin-1 in primary astrocytes