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Chemical and Pharmaceutical Bulletin

Volumn 49, Issue 3, 2001, Pages 268-277

Orally active GPIIb/IIIa antagonists: Synthesis and biological activities of masked amidines as prodrugs of 2-[(3S)-4-[(2S)-2-(4-amidinobenzoylamino)-3-(4-methoxyphenyl)propanoyl]-3- (2-methoxy-2-oxoethyl)-2-oxopiperazinyl]acetic acid

(6) Kitamura, S a Fukushi, H a Miyawaki, T a Kawamura, M a Terashita, Z I a Naka, T a

a TAKEDA PHARMACEUTICAL COMPANY LIMITED (Japan)

Author keywords

Antiplatelet effect; GPIIb IIIa antagonist; Masked amidine; Prodrugs for arylamidines

Indexed keywords

2 [4 [2 (4 AMIDINOBENZOYLAMINO) 3 (4 METHOXYPHENYL)PROPANOYL] 3 (2 METHOXY 2 OXOETHYL) 2 OXOPIPERAZINYL]ACETIC ACID; AMIDINE; FIBRINOGEN RECEPTOR ANTAGONIST; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; GUINEA PIG; MALE; NONHUMAN; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION INHIBITION;

ACETATES; AMINO ACIDS; ANIMALS; BINDING SITES; GUINEA PIGS; INDICATORS AND REAGENTS; MALE; MOLECULAR CONFORMATION; PIPERAZINES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035087137 PISSN: 00092363 EISSN: None Source Type: Journal
DOI: 10.1248/cpb.49.268 Document Type: Article

Times cited : (29)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.