Enhanced acetylcholine release in the hippocampus of cannabinoid CB1 receptor-deficient mice

British Journal of Pharmacology

Volumn 132, Issue 6, 2001, Pages 1169-1173

  Kathmann, Markus ^a   Weber, Bernd ^a   Zimmer, Andreas ^a   Schlicker, Eberhard ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Acetylcholine release; C57BL 6J mouse; Hippocampus; Mouse; Noradrenaline release; Presynaptic receptors; Septohippocampal pathway; SR 141716; Striatum

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ACETYLCHOLINE; CANNABINOID 1 RECEPTOR; NORADRENALIN; RIMONABANT;

ACETYLCHOLINE RELEASE; ANIMAL TISSUE; ARTICLE; CHOLINERGIC NERVE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG MECHANISM; ELECTROSTIMULATION; HIPPOCAMPUS; IN VIVO STUDY; MOUSE; NONHUMAN; NORADRENALIN RELEASE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; REPORTER GENE;

EID: 0035083860     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703987     Document Type: Article

References (21)

1. 1 receptor agonists increase rat cortical and hippocampal acetylcholine release in vivo
2. The effects of cannabinoids on the brain
3. The development of cannabinoid antagonists
4. Blockade of presynaptic α-receptors and of amine uptake in the rat brain by the antidepressant mianserine
5. Cannabinoid-induced working memory impairment is reversed by a second generation cholinesterase inhibitor in rats
6. Inhibition of hippocampal acetylcholine release by cannabinoids: Reversal by SR 141716A
7. Electrically evoked acetylcholine release from hippocampal slices is inhibited by the cannabinoid receptor agonist, WIN 55,212-2, and is potentiated by the cannabinoid antagonist, SR 141716 A
8. Cannabinoids, hippocampal function and memory
9. 1 receptor-mediated inhibition of acetylcholine release in the brain of NMRI, CD-1 and C57BL/6J mice
10. 1 receptor knockout mice
11. SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats
12. 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism
13. Endocannabinoids
14. 2 receptors
15. 1 receptor knock-out mice
16. The release of labelled acetylcholine and choline from cerebral cortical slices stimulated electrically
17. 1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus
18. Cannabinoid receptor interactions with the antagonists SR 141716A and SR 144528
19. Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids
20. Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716
21. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice