Can we reliably use markers of cell cycle regulation (e.g. Ki-67, p21, p27, p53) to differentiate between benign and malignant skin tumors?

Journal of Cutaneous Pathology

Volumn 28, Issue 4, 2001, Pages 219-221

  Murphy, M ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN; PROTEIN P21; PROTEIN P27; PROTEIN P53; TUMOR MARKER;

CANCER DIAGNOSIS; CELL CYCLE; CELLULAR DISTRIBUTION; DIFFERENTIAL DIAGNOSIS; GENE CONTROL; GENE DISRUPTION; IMMUNOPHENOTYPING; KERATINOCYTE; LETTER; SKIN CANCER; SKIN TUMOR;

CELL CYCLE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DIAGNOSIS, DIFFERENTIAL; HUMANS; KI-67 ANTIGEN; NEOPLASMS; PROLIFERATING CELL NUCLEAR ANTIGEN; REPRODUCIBILITY OF RESULTS; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035083589     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0560.2001.028004219.x     Document Type: Letter

References (14)

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3. Prognostic value of Ki67 antigen expression in basal cell carcinomas
4. Autoradiographic analysis of cell kinetics in human normal epidermis and basal cell carcinoma
5. In vitro DNA synthesis of keratinocytes in normal human skin, psoriasis, seborrhoeic keratosis, Bowen's disease and basal cell carcinoma
6. Cell proliferation and p53 protein expressions in cutaneous epithelial neoplasms
7. Immunohistochemical nuclear staining for p53, PCNA, and Ki-67 in different histologic variants of basal cell carcinoma
8. Cell proliferation in human basal cell carcinoma
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10. Ki-67 antigen expression and growth pattern of basal cell carcinomas
11. Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia
12. Hypoxia upregulates p27 in solid tumors
13. Molecular pathology in basal cell cancer with p53 as a genetic marker
14. The tumor microenvironment: A double-edged sword