Diagnosing visceral leishmaniasis with the recombinant K39 strip test: Experience from the Sudan

Tropical Medicine and International Health

Volumn 6, Issue 2, 2001, Pages 108-113

  Zijlstra, E E ^a,d   Nur, Y ^b   Desjeux, P ^c   Khalil, E A G ^a   El Hassan, A M ^a   Groen, J ^b  

^a UNIVERSITY OF KHARTOUM   (Sudan)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c WORLD HEALTH ORGANIZATION   (Switzerland)

^d UNIVERSITY OF MALAWI   (Malawi)

Author keywords

Diagnosis; rK39 strip test; Sudan; Visceral leishmaniasis

Indexed keywords

COLLOIDAL GOLD; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; PROTEIN A; RECOMBINANT ANTIGEN; RECOMBINANT K39 ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ENZYME LINKED IMMUNOSORBENT ASSAY; FOLLOW UP; HUMAN; LEISHMANIA; MAJOR CLINICAL STUDY; SKIN TEST; SUDAN; VISCERAL LEISHMANIASIS;

ADOLESCENT; ADULT; AGGLUTINATION TESTS; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BONE MARROW; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LYMPH NODES; MALE; MIDDLE AGED; PROTOZOAN PROTEINS; REAGENT STRIPS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; SPLEEN; SUDAN; TIME FACTORS;

LEISHMANIA MAJOR; PROTOZOA;

EID: 0035083343     PISSN: 13602276     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3156.2001.00680.x     Document Type: Article

References (18)

1. rK39: A cloned antigen of Leishmania chagasi that predicts active visceral leishmaniasis
2. Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis
3. Recent observations on the epidemiology of kala-azar in the Eastern and Central States of the Sudan
4. A comparison of the direct agglutination test and enzyme-linked sorbent assay in the serodiagnosis of leishmaniasis in the Sudan
5. High levels of plasma IL-10 and expression of Il-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis
6. Improvement of a direct agglutination test for field studies of visceral leishmaniasis
7. Evaluation of cleaving agents other than trypsin in Direct Agglutination Test for further improving diagnosis of visceral leishmaniasis
8. Leish-KIT, a stable direct agglutination test based on freeze-dried antigen for serodiagnosis of visceral leishmaniasis
9. Epidemic visceral leishmaniasis in southern Sudan
10. Serodiagnosis of Asian leishmaniasis with a recombinant antigen from the repetitive domain of a Leishmania kinesin
11. Diagnostic and prognostic value of K39 recombinant antigen in Indian leishmaniasis
12. Rapid accurate field diagnosis of visceral leishmaniasis
13. Direct Agglutination test for diagnosis and sero-epidemiological survey of kala-azar in the Sudan
14. Kala-azar in displaced people from southern Sudan: Epidemiological, clinical and therapeutic findings
15. Kala-azar: A comparative study of parasitological methods and the direct agglutination test in diagnosis
16. Endemic kala-azar in eastern Sudan: A longitudinal study on the incidence of clinical and subclinical disease and post-kala-azar dermal leishmaniasis
17. The direct agglutination test for diagnosis of visceral leishmaniasis under field conditions in Sudan: Comparison of aqueous and freeze-dried antigens
18. rK39 enzyme-linked immunosorbent assay for the diagnosis of L. donovani infection