Deprotonation of hydrochloride salts of amino acid esters and peptide esters using commercial zinc dust

Journal of Peptide Research

Volumn 57, Issue 3, 2001, Pages 223-226

  Ananda, K ^a   Suresh Babu, V V ^a  

^a BANGALORE UNIVERSITY   (India)

Author keywords

Activated zinc dust; Amino acid esters; Boc chemistry; Deprotonation; Free peptide esters; No base coupling

Indexed keywords

AMINO ACID DERIVATIVE; ESTER DERIVATIVE; PEPTIDE DERIVATIVE; ZINC;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OUTCOMES RESEARCH; PRIORITY JOURNAL;

AMINO ACIDS; BIOCHEMISTRY; ESTERS; PEPTIDES; SALTS; ZINC;

EID: 0035083123     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2001.00790.x     Document Type: Article

References (18)

1. Effect of tertiary bases on O-benzotriazolyluronium salt-induced peptide segment coupling
2. Coupling in the absence of tertiary amines
3. Coupling in the absence of tertiary amines: II
4. Acceptors in the removal of protecting groups
5. Coupling in the absence of tertiary amines: IV. Tetrazole as acidolytic reagent
6. Coupling in the absence of tertiary amines: V
7. A proposal for using mild bases in the preparation of optically pure peptides
8. Effect of tertiary amines and amine salts on racemization in peptide synthesis
9. Racemization during aminolysis of mixed and symmetrical anhydrides of N-alkoxycarbonylamino acids by amino acid anions in aqueous dimethylformamide
10. Racemization during aminolysis of activated esters of N-alkoxycarbonylamino acids by amino acid anions in partially aqueous solvents and a tactic to minimise it
11. Synthesis of peptides employing Fmoc-amino acid chlorides and commercial zinc dust
12. Synthesis of peptides employing Fmoc-/Boc-/ Z-amino acid fluorides and activated commercial zinc dust
13. Amino acids and peptides. Part XXVIII. Determination of racemization in peptide synthesis by nuclear magnetic resonance spectroscopy