A seminested PCR test for simultaneous detection of two common mutations (35delG and 167delT) in the connexin-26 gene

Molecular Diagnosis

Volumn 6, Issue 1, 2001, Pages 63-67

  Simsek, Mehmet ^a   Al Wardy, Nadia ^a   Al Khabory, Mazin ^b  

^a SULTAN QABOOS UNIVERSITY   (Oman)

^b Al Nahda Hospital   (Oman)

Author keywords

35delG and 167delT mutations; Connexin 26 gene (GJB2); Deafness

Indexed keywords

CONNEXIN 26; DNA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE; GENE MUTATION; HEARING IMPAIRMENT; HUMAN; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 0035081453     PISSN: 10848592     EISSN: None     Source Type: Journal    
DOI: 10.1054/modi.2001.22119     Document Type: Article

References (15)

1. Genetic epidemiology of hearing impairment
2. Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
3. Connexin-26 mutations in sporadic and inherited sensorineural deafness
4. Connexin-26 mutations associated with the most common form of non-syndromic neurosensory autosomal recessive deafness (DFNB1) in Mediterraneans
5. Prelingual deafness: High prevalence of a 30delG mutation in the connexin-26 gene
6. Mutations in the connexin 26 gene (GJB2) among Ashkenazi Jews with nonsyndromic recessive deafness
7. Clinical studies of families with hearing loss attributable to mutations in the connexin-26 gene (GJB2/DFNB1)
8. Allele specific oligonucleotide analysis of the common deafness mutation 35delG in the connexin 26 gene (GJB2)
9. Determination of the carrier frequency of the common GJB2 (connexin-26) 35delG mutation in the Belgian population using an easy and reliable screening method
10. A simple PCR test to detect the common 35delG mutation in the connexin-26 gene
11. A simple salting out procedure for extracting DNA from human nucleated cells
12. Optimization of the polymerase chain reaction
13. Pitfalls in N-acetyltransferase 2 genotyping
14. Prevalent connexin 26 gene (GJB2) mutations in Japanese
15. Connexin-26 mutations associated with nonsyndromic hearing loss