No effect of L-arginine supplementation on pulmonary endothelial dysfunction after cardiopulmonary bypass

Acta Anaesthesiologica Scandinavica

Volumn 45, Issue 4, 2001, Pages 441-448

  Angdin, M ^a   Settergren, G ^a   Liska, J ^a   Astudillo, R ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Acetylcholine; Cardiopulmonary bypass; L arginine; Nitric oxide; Pulmonary circulation; Reperfusion injury; Vascular resistance

Indexed keywords

ACETYLCHOLINE; ARGININE; NITRIC OXIDE; PLACEBO;

ADULT; AGED; ARTICLE; BRONCHOSPASM; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENDOTHELIUM LESION; FEMALE; HEART MUSCLE REPERFUSION; HUMAN; ISCHEMIC HEART DISEASE; LUNG VASCULAR RESISTANCE; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REPERFUSION INJURY; TACHYCARDIA; TREATMENT OUTCOME; VALVULAR HEART DISEASE;

ACETYLCHOLINE; ADULT; AGED; AGED, 80 AND OVER; ARGININE; CARDIAC OUTPUT; CARDIOPULMONARY BYPASS; DOUBLE-BLIND METHOD; ENDOTHELIUM, VASCULAR; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; PULMONARY CIRCULATION; STROKE VOLUME; VASCULAR RESISTANCE;

EID: 0035079991     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.2001.045004441.x     Document Type: Article

References (22)

1. Nitric oxide: Physiology, pathophysiology, and pharmacology
2. Coronary artery endothelial function after myocardial ischemia and reperfusion
3. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
4. Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilatation in the lung
5. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
6. Pulmonary artery endothelial dysfunction following ischemia and reperfusion of the rabbit lung
7. Alteration of the neonatal pulmonary physiology after total cardiopulmonary bypass
8. Intracoronary L-arginine during reperfusion improves endothelial function and reduces infarct size
9. Attenuation of myocardial ischemia-reperfusion injury with nitric oxide replacement therapy
10. Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium
11. L-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle
12. L-arginine administration during reperfusion improves pulmonary function
13. L-arginine and pentoxifylline attenuate endothelial dysfunction after lung reperfusion injury in the rabbit
14. L-arginine minimizes reperfusion injury in a low flow, reflow model of liver perfusion
15. Quenching the effects of L-arginine on free radical injury in cultured cardiomyocytes
16. Supplemental L-arginine during cardioplegic arrest and reperfusion avoids regional postischemic injury
17. Direct detrimental effects of L-arginine upon ischemia-reperfusion injury to myocardium
18. Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass
19. Altered reactivity to acetylcholine in the pulmonary circulation after cardio-pulmonary bypass is part of reperfusion injury
20. Acetylcholine reactivity in the pulmonary artery during open heart surgery in patients with ischemic and/or valvular heart disease
21. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
22. A fatal overdose of arginine hydrochloride