Effects of fluoroquinolones on the locomotor activity in rats

Archives of Toxicology

Volumn 75, Issue 1, 2001, Pages 36-41

  Thiel, Renate ^a,b   Metzner, Stefanie ^a   Gericke, Christine ^a   Rahm, Ute ^a   Stahlmann, Ralf ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Behaviour; Fluoroquinolones; Neurotoxicity; Pharmacokinetics; Rats

Indexed keywords

FLEROXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSOMNIA; LOCOMOTION; MALE; MOTOR ACTIVITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SOMNOLENCE; TASK PERFORMANCE; VERTIGO;

ADMINISTRATION, ORAL; AGE FACTORS; ANIMALS; ANTI-INFECTIVE AGENTS; BODY WEIGHT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME INHIBITORS; FEMALE; FLEROXACIN; FLUOROQUINOLONES; LOCOMOTION; MALE; NAPHTHYRIDINES; OFLOXACIN; PHOTIC STIMULATION; RATS; RATS, WISTAR; TIME FACTORS;

ANIMALIA;

EID: 0035079359     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040000207     Document Type: Article

References (19)

1. Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
2. Structure-epileptogenicity relationship of quinolones with special reference to their interaction with γ-aminobutyric acid receptor sites
3. Chromatographische bestimmung von ofloxacin in körperflüssigkeiten
4. Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin
5. Adverse reactions to fluoroquinolones in adults and children
6. Fleroxacin: A review of its chemistry, microbiology, toxicology, pharmacokinetics, clinical efficacy and safety
7. Effects of some excitatory amino acid antagonists and drugs enhancing γ-aminobutyric acid neurotransmission on pefloxacin-induced seizures in DBA/2 mice
8. Quinolone-induced cartilage lesions are not reversible in rats
9. Fluoroquinolone toxicity profiles: A review focusing on newer agents
10. Pharmacokinetics of ofloxacin after parenteral and oral administration
11. In vivo assessment of prevention of white-noise-induced seizure in magnesium-deficient rats by N-methyl-D-aspartate receptor blockers
12. Determination of the excitatory potencies of fluoroquinolones in the central nervous system by an in vitro model
13. Quinolones do not interact with NMDA receptor in dissociated rat hippocampal neurons
14. Toxicity of quinolones
15. Ofloxacin in juvenile non-human primates and rats. Arthropathia and drug plasma concentrations
16. Toxicity of quinolone antimicrobial agents
17. Oral bioavailability of trovafloxacin with and without food in healthy volunteers
18. Device for monitoring locomotor activity of 120 animals: Motility of offspring of dams exposed to haloperidol
19. Sleep disturbance in children treated with ofloxacin