Functional, structural, and genetic mitochondrial abnormalities in myocardial diseases

Journal of Nuclear Cardiology

Volumn 8, Issue 1, 2001, Pages 89-97

  Brega, Agnese ^a   Narula, Jagat ^b   Arbustini, Eloisa ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b Heart Failure/Transplant Program   (United States)

^c FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CELL NUCLEUS DNA; HEART ENZYME; MITOCHONDRIAL DNA; MYOSIN HEAVY CHAIN; RIBOSOME RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DNA DETERMINATION; DNA STRUCTURE; DNA SYNTHESIS; ENERGY CONSUMPTION; ENZYME ACTIVITY; GENE MUTATION; GENETIC ANALYSIS; HEART FUNCTION; HEART MITOCHONDRION; HEART MUSCLE; HEART MUSCLE BIOPSY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MOLECULAR BIOLOGY; MOUSE; MUSCLE CELL; MYOCARDIAL DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0035077977     PISSN: 10713581     EISSN: None     Source Type: Journal    
DOI: 10.1067/mnc.2001.112755     Document Type: Article

References (50)

1. Mitochondrial diseases in man and mouse
2. Mitochondrial DNA mutations in human diseases. A review
3. Mitochondrial biogenesis in striated muscle
4. Ultrastructural pathology of the heart
5. Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man
6. Mitochondrial evolution
7. Mitochondrial DNA variation in human evolution and disease
8. Using mitochondrial and nuclear DNA markers to reconstruct human evolution
9. Sequence and organization of the human mitochondrial genome
10. Mitochondrial DNA. Maintenance in vertebrates
11. Duplications of mitochondrial DNA: Implications for pathogenesis
12. Regulation of mitochondrial gene expression in mammalian cells
13. tRNA punctuation model of RNA processing in human mitochondria
14. Synthesis and turnover of mitochondrial nucleic acid in HeLa cells: The mature ribosomal and messenger ribonucleic acid species are metabolically unstable
15. Maternal inheritance of human mitochondrial DNA
16. Rapid evolution of animal mitochondrial DNA
17. Polymorphic sites and mechanism of evolution in human mitochondrial DNA
18. Intraspecific nucleotide sequence differences in the major non coding region of human mitochondrial DNA
19. Repair of mtDNA in vertebrates
20. Mitochondrial DNA in human pathology
21. Endomyocardial biopsy
22. Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy
23. Coexistence of mitochondrial DNA and myosin heavy chain mutations in hypertrophic cardiomyopathy with late congestive heart failure
24. Myoclonic epilepsy and ragged red fiber disease (MERRF) is associated with a mitochondrial tRNALys mutations
25. Age-dependent increase in deleted mitochondrial DNA in the human heart: Possible contributory factor to "presbycardia"
26. Hypertrophic cardiomyopathy with mitochondrial DNA depletion and respiratory enzyme defects
27. An additional mitochondrial tRNAIle point mutation (A-to-G at nucleotide 4295) causing hypertrophic cardiomyopathy
28. Point mutations in mitochondrial DNA of patients with dilated cardiomyopathy
29. Point mutations in mitochondrial DNA in patients with hypertrophic cardiomyopathy
30. Cardiac involvement in mitochondrial diseases: A study of 17 patients with mitochondrial DNA defects
31. The mitochondrial A3243G mutation presenting as severe cardiomyopathy
32. Maternally inherited myopathy and cardiomyopathy: Association with mutation in mitochondrial DNA tRNALeu(UUR)
33. Mitochondrial DNA mutations and bioenergetic defects in aging and degenerative diseases
34. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
35. MITO-MAP: A human mitochondrial genome database 1998-update
36. A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
37. A deficiency of carnitine-acylcarnitine translocase in the inner mitochondrial membrane
38. Disorders associated with defects of beta-oxidation
39. Familial cardiomyopathy with cataracts and lactic acidosis: A defect in complex I (NADH dehydrogenase) of the mitochondria respiratory chain
40. Clinical heterogeneity in respiratory chain complex III deficiency in childhood
41. Cardiomyopathy in Friedreich ataxia: A Doppler-echocardiographic study
42. Apoptosis in heart failure: Release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy
43. Mitochondrial DNA complex I and III mutations associated with Leber's hereditary optic neuropathy
44. Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients
45. Human molecular genetics
46. A new mutation associated with MELAS is located in a mitochondrial DNA polypeptide-coding gene
47. Double heterozygosity for mutations in the beta-myosin heavy chain and in the cardiac myosin binding protein C genes in a family with hypertrophic cardiomyopathy
48. Two cases of prenatal analysis for the pathogenic T to G substitution at nucleotide 8993 in mitochondrial DNA
49. Evidence-based diagnosis of familial non-X linked dilated cardiomyopathy. Prevalence, inheritance and characteristics