Pharmacological and physiological effects of ginseng on actions induced by opioids and psychostimulants

Folia Pharmacologica Japonica

Volumn 117, Issue 3, 2001, Pages 195-201

  Tokuyama, Shogo ^a   Takahashi, Masakatsu ^b  

^a SHOWA UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

Ginseng; Opioid; Psychic physical dependence; Psychostimulant; Tolerance

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZAMIDE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; COCAINE; METHAMPHETAMINE; MORPHINE; OPIATE; PSYCHOSTIMULANT AGENT;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG EFFECT; DRUG MECHANISM; GINSENG; MENTAL STRESS; MORPHINE TOLERANCE; MOUSE; NONHUMAN; PLACE PREFERENCE;

ANALGESICS, OPIOID; ANIMALS; CONDITIONING (PSYCHOLOGY); DRUG TOLERANCE; DRUGS, CHINESE HERBAL; GINSENOSIDES; HUMANS; LIPOPOLYSACCHARIDES; PANAX; PLANTS, MEDICINAL; PSYCHOTROPIC DRUGS; SAPONINS; SUBSTANCE-RELATED DISORDERS;

EID: 0035077906     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.117.195     Document Type: Article

References (42)

1. Antagonism of the acute pharmacological actions of morphine by Panax ginseng extract
2. The effect of Panax ginseng on the development of tolerance to the pharmacological actions of morphine in the rat
3. The possible involvement of GABAA systems in the antinarcotic effect of majonoside-R2, a major constituent of Vietnamese ginseng, in mice
4. Majonoside-R2, a major constituent of Vietnamese ginseng, attenuates opioid-induced antinociception
5. Antagonism of U-50,488H-induced antinociception by ginseng total saponins is dependent on serotonergic mechanisms
6. The GTP-binding protein, Go, regulates neuronalcalcium channels
7. Ginseng root extract inhibits calcium channels in rat sensory neurons through a similar path, but different receptor, as mu-type opioids
8. Effects of Panax ginseng on the development of morphine tolerance and dependence
9. Antinarcotic effects of the standardized ginseng extract G115 on morphine
10. Anti-effect of ginseng on the inhibition of the development of morphine tolerance in stressed mice
11. Influence of ginseng on the stress mechanism
12. Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot shock stress-induced antinociception in mice
13. Effects of vietnamese ginseng on opioid agonist- and conditioned fear stress-induced antinociception
14. Blockade of the development of analgesic tolerance to morphine by concurrent treatment with opioid- but not non-opioid-mediated stress in mice
15. Blockade of the development of analgesic tolerance to morphine by psychological stress through benzodiazepine receptor mediated mechanism
16. Effect of ginseng saponin on rat adrenal cyclic AMP
17. Role of adrenal glucocorticoids in the blockade of the development of analgesic tolerance to morphine by footshock stress exposure in mice
18. Effect of the saponin fraction of Panax ginseng on catecholamines in mouse brain
19. Effects of stress on the metabolism of norepinephrine, dopamine and serotonin in the central nervous system of the rat. 1. Modifications of norepinephrine turnover
20. Psychological stress enhances noradrenaline turnover in specific brain regions in rats
21. Action site of adrenergic blockers to suppress the development of tolerance to morphine analgesia
22. Effects of the ginsenosides Rg1 and Rb1 on morphine-induced hyperactivity and reinforcement in mice
23. Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice
24. Inhibition by ginseng total saponin of the development of morphine reverse tolerance and dopamine receptor supersensitivity in mice
25. Blockade by ginseng total saponin of the development of methamphetamine reverse tolerance and dopamine receptor supersensitivity in mice
26. Blockade by ginseng total saponin of the development of cocaine induced reverse tolerance and dopamine receptor supersensitivity in mice
27. Blockade by ginseng extract of the development of reverse tolerance to the ambulation-accelelating effect of methamphetamine in mice
28. The effect of ginseng extract on locomotor sensitization and conditioned place preference induced by methamphetamine and cocaine in mice
29. Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
30. Cocaine-induced behavioral sensitization and D1 dopamine receptor function in rat nucleus accumbens and striatum
31. Ginseng saponins: Influence on neurotransmitter uptake in rat brain synaptosomes
32. Conditioned place preference as a measure of drug reward
33. Inhibition by ginsenosides Rb1 and Rg1 of methamphetamine-induced hyperactivity, conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice
34. Blockade by ginseng total saponin of methamphetamine-induced hyperactivity and conditioned place preference in mice
35. Analysis of ginseng I
36. Analysis of ginseng II
37. Effects of the administration of coca alkaloids on the primary immune responses of mice: Interaction with delta-9-tetrahydrocannabinol and ethanol
38. Cocaine immunotoxicity: Abnormal cytokine production in hispanic drug users
39. Modulation of tumor necrosis factor and gamma interferon production by cocaine and morphine in aging mice infected with LP-BM5, a murine retrovirus
40. Effects of lipopolysaccharide from Pantoea agglomerans on the cocaine-induced place preference
41. The effect of polysaccharides of root of Panax ginseng on the immune function
42. Effects of ginseng polysaccharides on tumor and immunological function in tumor-bearing mice