Overexpression of vascular endothelial growth factor C is related to lymphogenous metastasis in early gastric carcinoma

Oncology

Volumn 60, Issue 2, 2001, Pages 146-150

  Kabashima, Akira ^a   Maehara, Yoshihiko ^a   Kakeji, Yoshihiro ^a   Sugimachi, Keizo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Early gastric carcinoma; Lymphogenous metastasis; Vascular endothelial growth factor; Vascular endothelial growth factor C

Indexed keywords

MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN C;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER INVASION; CLINICAL FEATURE; CONTROLLED STUDY; EARLY CANCER; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STOMACH CARCINOMA;

AGED; ANTIBODIES, MONOCLONAL; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; STOMACH NEOPLASMS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 0035077659     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000055312     Document Type: Article

References (24)

1. Pathological appearance of the stomach after endoscopical mucosal resection for early gastric cancer
2. Early carcinoma of the stomach
3. Early gastric carcinoma with special reference to macroscopic classification
4. Development of strip-off biopsy
5. Clinical significance of occult micrometastasis in lymph nodes from patients with early gastric cancer who died of recurrence
6. Metastasizing intramucosal gastric carcinomas
7. Lymph node metastasis in early gastric cancer
8. Clinicopathological features of mucosal carcinoma of the stomach with lymph node metastasis in eleven patients
9. Angiogenesis
10. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
11. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
12. Lymph and blood capillaries of the human gastric mucosa: A morphologic basis for metastasis in early gastric carcinoma
13. Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasis
14. Vascular endothelial growth factor-C expression in the development of lymph node metastasis in gastric cancer
15. Vascular permeability factor/vascular endothelial growth factor, microvascular hyper-permeability, and angiogenesis
16. The biology of vascular endothelial growth factor
17. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
18. Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)
19. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
20. FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines
21. VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
22. Vascular endothelial growth factor C induces angiogenesis in vivo
23. Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia