HLA class II associations with Type 1 diabetes mellitus: A multivariate approach

Tissue Antigens

Volumn 57, Issue 2, 2001, Pages 144-150

  Schipper, R F ^a   Koeleman, B P C ^a   Bruining, G J ^b   Schreuder, G M Th ^a   Verduijn, W ^a   De Vries, R R P ^a   Roep, B O ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

HLA class II; Insulin dependent diabetes mellitus; Multivariate analysis

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN;

ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HAPLOTYPE; HLA SYSTEM; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; NETHERLANDS; PHENOTYPE; PRIORITY JOURNAL; RISK ASSESSMENT;

DIABETES MELLITUS, TYPE 1; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MULTIVARIATE ANALYSIS; ODDS RATIO; PHENOTYPE;

EID: 0035077207     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0039.2001.057002144.x     Document Type: Article

References (36)

1. HL-A antigens and diabetes mellitus
2. Evidence for HL-A·linked genes in "juvenile" diabetes mellitus
3. Heterozygous expression of insulin-dependent diabetes mellitus (IDDM) determinants in the HLA system
4. Lawrence Lecture. The Emperor's new genes: 1993 RD Lawrence Lecture
5. Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping
6. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: A family study
7. A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles
8. HLA and insulin-dependent diabetes: An overview
9. Relative contribution of HLA-DQA and -DQB alleles to predisposition to insulin-dependent diabetes mellitus
10. The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci
11. Susceptibility to type I diabetes: HLA-DQ and DR revisited
12. HLA-encoded genetic predisposition in DDM: DR4 subtypes may be associated with different degrees of protection
13. Distribution of HLA-DRB1, -DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus
14. Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia
15. HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families
16. The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian, multiplex families
17. Different contribution of HLA-DR and -DQ genes in susceptibility and resistance to insulin-dependent diabetes mellitus (IDDM)
18. Combinations of HLA DR and DQ molecules determine the susceptibility to insulin-dependent diabetes mellitus in Koreans
19. Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus
20. Analysis of factorial arrangements when the data are proportions
21. An exploratory technique for investigating large quantities of categorical data
22. Can we really predict IDDM?
23. HLA-DRB1*0403 is associated with dominant protection against IDDM in the general Dutch population and subjects with highrisk DQA1*0301- DQB1*0302/DQA1*0501-DQB1*0201 genotype
24. HLA gene and haplotype frequencies in Dutch blood donors
25. Automated reading of Propidium Iodide lymphocytotoxicity tests for HLA-DR, MB, MT typing
26. The estimation and significance of the logarithm of a ratio of frequencies
27. On estimating the relation between blood group and disease
28. HL-A and disease. The detection of associations
29. Genetic structure of IDDM1: Two separate regions in the major histocompatibility complex contribute to susceptibility or protection. Belgian Diabetes Registry
30. Transcomplementation of HLA DQA1-DQB1 in DR3/DR4 and DR3/DR9 heterozygotes and IDDM in Taiwanese families
31. Association of HLA-DR phenotypes and T-lymphocyte-receptor beta-chain-region RFLP with IDDM in Japanese
32. Association of HLA-DR, DQ genotype with different beta-cell functions at IDDM diagnosis in Japanese children
33. Particular HLA-DQ alpha beta heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites
34. Analysis of critical residues of HLA-DQ6 molecules in insulin-dependent diabetes mellitus