EMLA anaesthetic cream for sharp leg ulcer debridement: A review of the clinical evidence for analgesic efficacy and tolerability

European Journal of Dermatology

Volumn 11, Issue 2, 2001, Pages 90-96

  Vanscheidt, W ^a   Sadjadi, Z ^a   Lillieborg, S ^a  

^a Clinic for Wound Biology   (Germany)

Author keywords

Analgesia; Leg ulcer; Lidocaine; Plasma level; Prilocaine; Topical administration

Indexed keywords

EMLA; PLACEBO;

ANALGESIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEBRIDEMENT; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; HEALTH CARE COST; HUMAN; HUMAN CELL; HUMAN TISSUE; INCIDENCE; LEG ULCER; MAJOR CLINICAL STUDY; META ANALYSIS; PATIENT SATISFACTION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; REVIEW;

ADMINISTRATION, CUTANEOUS; ANESTHETICS, LOCAL; CLINICAL TRIALS; DEBRIDEMENT; HUMANS; LEG ULCER; LIDOCAINE; PAIN; PAIN MEASUREMENT; PRILOCAINE; RANDOMIZED CONTROLLED TRIALS;

EID: 0035076628     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (44)

1. Chronic ulceration of the leg: Extent of the problem and provision of care
2. Venous leg ulceration: Treatment by high compression bandaging
3. Quality of life in chronic leg ulcer patients
4. A study of the impact of leg ulcers on quality of life: Financial, social and psychologic implications
5. Venous leg ulcers: Is pain a problem?
6. Pain in venous leg ulcers
7. Living with a venous leg ulcer: A descriptive study of patients' experiences
8. Repeated treatment with lidocaine/prilocaine cream (EMLAs®) a topical anaesthetic for the cleansing of venous leg ulcers: A controlled study
9. Current management of leg ulcers
10. Effect of extensive debridement and treatment on the healing of diabetic foot ulcers
11. Wound debridement, Part 2: Sharp techniques
12. Guidelines for the management of chronic venous leg ulceration. Report of a multidisciplinary workshop
13. Pinchgrafting for chronic venous leg ulcers in general practice
14. Leg ulcers. Diagnosis and treatment. Södertälje
15. Stimulation of repair in chronic, nonhealing, cutaneous ulcers using platelet-derived wound healing formula
16. Surgical debridement versus enzymatic debridement - Benefits and drawbacks
17. Chronisch-venöse insuffizienz - Von der pathophysiologie zur therapie. Folge 4: Behandlung des ulcus cruris - Therapierichtlinien
18. EMLA cream as a topical anesthetic for the repeated mechanical debridement of venous leg ulcers: A double-blind, placebo-controlled study
19. Norwegian Medicines Control Authority, Oslo, Norway and Medical Products Agency, Uppsala, Sweden: Workshop
20. Diseases of the veins and arteries: Leg ulcers
21. Lidocaine-prilocaine cream (EMLA creams®) as a topical anaesthetic for the cleansing of leg ulcers: The effect of length of application time
22. EMLA: A new topical anesthetic
23. Local anesthesia of the genital mucosa with a lidocaine/prilocaine cream (EMLA) for laser treatment of condylomata acuminata: A placebo-controlled study
24. Pain control in the surgical debridement of leg ulcers by the use of a topical lidocaine-prilocaine cream, EMLA®
25. Plasma concentrations and analgesic effect of EMLA (lidocaine/prilocaine) cream for the cleansing of leg ulcers
26. Perkutane anästhesie beim debridement venöser unterschenkeluzera
27. Analgesic effect and local reactions of repeated application of EMLA® (lidocaine/prilocaine) cream for the cleansing of leg ulcers
28. EMLA cream as a topical anaesthetic for ulcer debridement and simultaneous split-skin grafting
29. Using o topical anaesthetic cream to reduce pain during sharp debridement of chronic leg ulcers
30. EMLA anaesthetic cream for sharp debridement of venous leg ulcers. A double-blind, placebo-controlled study
31. 2-Laser
32. Graphic representation of pain
33. Contact allergy and cross-reactions caused by prilocaine
34. Allergic contact dermatitis from prilocaine, one of the local anaesthetics in EMLA® cream
35. Patch testing in suspected allergic contact dermatitis due to EMLA® cream in haemodialyzed patients
36. Emla cream-induced allergic contact dermatitis: A role for prilocaine as an immunogen
37. Adverse effects associated with EMLA cream used as topical anesthetic for the mechanical debridement of leg ulcers
38. Lignocaine kinetics in cardiac patients and aged subjects
39. Pharmacokinetics of local anaesthetics
40. Adverse effects associated with EMLA cream used as topical anesthetic for the mechanical debridement of leg ulcers
41. An open clinical study on plasma concentrations of lidocaine and prilocaine after application of EMLA® 5% cream to leg ulcers
42. Clinical pharmacology of local anesthetic agents