Calculating confidence intervals for the number needed to treat

Controlled Clinical Trials

Volumn 22, Issue 2, 2001, Pages 102-110

  Bender, Ralf ^a  

^a BIELEFELD UNIVERSITY   (Germany)

Author keywords

Absolute risk reduction; Confidence interval; Equivalence; Evidence based medicine; Number needed to treat

Indexed keywords

ARTICLE; CALCULATION; EVIDENCE BASED MEDICINE; PATIENT; STATISTICS;

CONFIDENCE INTERVALS; EVIDENCE-BASED MEDICINE; HUMANS; RANDOMIZED CONTROLLED TRIALS; SAMPLE SIZE;

EID: 0035074086     PISSN: 01972456     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-2456(00)00134-3     Document Type: Article

References (34)

1. The number needed to treat: A clinically useful measure of treatment effect
2. On some clinically useful measures of the effects of treatment
3. The number needed to treat: A clinically useful nomogram in its proper context
4. Confidence intervals for the number needed to treat
5. A note on the number needed to treat
6. Interval estimation for the difference between independent proportions: Comparison of eleven methods
7. Confidence limits made easy: Interval estimation using a substitution method
8. Comparative analysis of two rates
9. Asymptotic confidence intervals for the difference between binomial parameters for the use with small samples
10. A non-iterative accurate asymptotic confidence interval for the difference between two proportions
11. Computer software that can calculate confidence intervals is now available
12. Confidence intervals rather than P values: Estimating rather than hypothesis testing
13. Approximate is better than "exact" for interval estimation of binomial proportions
14. Confidence intervals for a binomial proportion
15. Two-sided confidence intervals for the single proportion: Comparison of seven methods
16. Periodic blood transfusions reduced the risk for stroke in children with sickle-cell anaemia
17. Captopril was not more effective than conventional treatment in hypertension and led to an increase in stroke
18. Vein-patch closure was better than primary closure in decreasing early strokes and arterial occlusion in carotid endarterectomy
19. Pravastatin reduced cardiovascular events in older patients with myocardial infarction and average cholesterol levels
20. Trials to assess equivalence: The importance of rigorous methods
21. Biostatistical methodology in clinical trials in applications for marketing authorizations for medical products
22. An assessment of clinically useful measures of the consequences of treatment
23. Using numerical results from systematic reviews in clinical practice
24. Number needed to screen: Development of a statistic for disease screening
25. Expressing the magnitude of adverse effects in case-control studies: "The number of patients needed to be treated for one additional patient to be harmed."
26. Number needed to treat: Absolute risk reduction may be easier for patients to understand
27. Number who benefit per unit of treatment may be a more appropriate measure
28. Confidence intervals for the number needed to treat: Absolute risk reduction is less likely to be misunderstood
29. Number needed to treat: Properties and problems
30. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
31. Tight blood pressure control reduced diabetes mellitus-related deaths and complications and was cost-effective in type 2 diabetes
32. Calculating the number needed to treat where the outcome is time to an event