Expression of vascular endothelial growth factor receptor 3 in blood and lymphatic vessels of lung adenocarcinoma

Journal of Pathology

Volumn 193, Issue 4, 2001, Pages 450-457

  Niki, Toshiro ^a   Iba, Sanae ^a   Yamada, Tesshi ^a   Matsuno, Yoshihiro ^a   Enholm, Berndt ^a   Hirohashi, Setsuo ^a,b  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Angiogenesis; Immunohistochemistry; Lung cancer; Lymphangiogenesis; Lymphatic invasion

Indexed keywords

BIOLOGICAL MARKER; CD31 ANTIGEN; EOSIN; FORMALDEHYDE; HEMATOXYLIN; KI 67 ANTIGEN; LAMININ; PARAFFIN; VASCULOTROPIN RECEPTOR;

ADULT; ARTICLE; BLOOD; BLOOD VESSEL; CANCER CELL; CANCER INVASION; CELL GROWTH; CELL LABELING; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; LYMPH NODE METASTASIS; LYMPH VESSEL; LYMPH VESSEL ENDOTHELIUM; MAJOR CLINICAL STUDY; MALE; PLEURA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; STAINING; STROMA; TISSUE FIXATION; TUMOR VASCULARIZATION; VASCULAR ENDOTHELIUM;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ENDOTHELIUM, LYMPHATIC; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; LYMPHATIC SYSTEM; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 0035073523     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.828     Document Type: Article

References (28)

1. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
2. Angiogenesis and metastasis
3. Lymphagenesis and cancer metastasis
4. Role of lymphagenesis in neovascularisation
5. Lack of lymphangiogenesis in human primary cutaneous melanoma. Consequences for the mechanism of lymphatic dissemination
6. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries. Podoplanin as a specific marker for lymphatic endothelium
7. Quantification of angiogenesis in solid human tumours: An international consensus on the methodology and criteria of evaluation
8. Signaling angiogenesis and lymphangiogenesis
9. Proteolytic processing regulates receptor specificity and activity of VEGF-C
10. Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity
11. Vascular endothelial growth factor C induces angiogenesis in vivo
12. Vascular endothelial growth factor-C (VEGF-C/VEGF-2) promotes angiogenesis in the setting of tissue ischemia
13. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
14. Avian VEGF-C: Cloning, embryonic expression pattern and stimulation of the differentiation of VEGFR2-expressing endothelial cell precursors
15. VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane
16. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
17. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
18. Expression of the fms-like tyrosine kinase 4 becomes restricted to lymphatic endothelium during development
19. Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3
20. Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis
21. Expression of the vascular endothelial growth factor C receptor VEGFR-3 in lymphatic endothelium of the skin and in vascular tumours
22. Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer
23. Vascular endothelial growth factor-C expression in human prostatic carcinoma and its relationship to lymph node metastasis
24. VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer
25. Relation of neovascularization to metastasis of non-small-cell lung cancer
26. Tumor angiogenesis in human lung adenocarcinoma
27. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB1 and MIB3) detect proliferating cells in microwave-processed formalin fixed paraffin sections