Effects of paeoniflorin on the formalin-induced nociceptive behaviour in mice

Journal of Ethnopharmacology

Volumn 75, Issue 2-3, 2001, Pages 267-271

  Tsai, Huei Yann ^a,b   Lin, Yuh Tzy ^a   Tsai, Chang Hai ^b   Chen, Yuh Fung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Antinociception; Formalin; Nociceptive behavior; Paeoniflorin

Indexed keywords

ARGININE; BETA FUNALTREXAMINE; CALCIUM; FORMALDEHYDE; KAPPA OPIATE RECEPTOR; MORPHINE; N(G) NITROARGININE METHYL ESTER; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NALOXONE; PAEONIFLORIN; RYANODINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; BEHAVIOR; CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; MALE; MOUSE; NOCICEPTION; NONHUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BENZOIC ACIDS; BRIDGED COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FORMALDEHYDE; GLUCOSIDES; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED ICR; PAIN;

EID: 0035073347     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(00)00403-7     Document Type: Article

References (20)

1. The effect of Veratri formosani rhizoma on some central actions of Paeoniae radix
2. G-nitro-L-arginine
3. Peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway
4. Analgesia by direct antagonism of nociceptor sensitization involves the arginine-nitric oxide-cGMP pathway
5. The formalin test: a quantitative study of the analgesic effects of morphine, meperdine, and brain stem stimulation in rats and cats
6. Blockade of hyperalgesia and neurogenic edema by topical application of nitroglycerin
7. Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in the rat
8. Studies on active substances in herbs used for oketsu ('stagnant blood') in Chinese medicine.VI. On the anticoagulative principle in paeoniae radix
9. Antinociceptive effect of L-arginine on carrageenin-induced hyperalgesia in rats: possible involvement of central opioidergic systems
10. L-Arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway
11. Anticholinergic action of paeony root and its active constituents
12. Molecular characterization of opioid receptor
13. Nitric oxide (NO) and nociceptive processing in the spinal cord
14. Is there a role for an endothelium-derived relaxing factor in nociception?
15. Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex
16. G-nitro-arginine methyl ester exhibits antinociceptive activity in the mouse
17. Modified formalin test: characteristic biphasic pain response
18. Opioid receptor knockout mice define μ opioid roles in endogenous nociceptive responses and morphine-induces analgesia
19. Effects of veratrine and paeoniflorin in mice by writhing response test
20. Role of nitric oxide/cyclic GMP in i.c.v. administered beta-endorphin-and (+)-cis-dioxolane-induced antinociception in the mouse