Preparation of spin-labeled 2-amino-dA, dA, dC and 5-methyl-dC phosphoramidites for the automatic synthesis of EPR active oligonucleotides

Synthesis

Volumn , Issue 4, 2001, Pages 565-572

  Giordano, C ^a   Fratini, F ^a   Attanasio, D ^a   Cellai, L ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

DNA; EPR; Nitroxides; Nucleosides; ODNs

Indexed keywords

FREE RADICALS; NUCLEIC ACIDS; PARAMAGNETIC RESONANCE; SPECTROSCOPY;

OLIGONUCLEOTIDES; PHOSPHORAMIDITES;

SYNTHESIS (CHEMICAL);

5' O (4,4' DIMETHOXYTRITYL) 2 ISOBUTYRAMIDO N 6 (1 OXYL 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL) 2' DEOXYADENOSINE 3' (2 CYANOETHYL N,N DIISOPROPYL)PHOSPHORAMIDITE; 5' O (4,4' DIMETHOXYTRITYL) 5 METHYL N 4 (1 OXYL 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL) 2' DEOXYCYTIDINE 3' (2 CYANOETHYL N,N DIISOPROPYL)PHOSPHORAMIDITE; 5' O (4,4' DIMETHOXYTRITYL) N 4 (1 OXYL 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL) 2' DEOXYCYTIDINE 3' (2 CYANOETHYL N,N DIISOPROPYL)PHOSPHORAMIDITE; 5' O (4,4' DIMETHOXYTRITYL) N 6 (1 OXYL 2,2,6,6 TETRAMETHYL 4 PIPERIDINYL) 2' DEOXYADENOSINE 3' (2 CYANOETHYL N,N DIISOPROPYL)PHOSPHORAMIDITE; FREE RADICAL; N,N,N TRIMETHYLTEMPAMINE; NITROXIDE; OLIGONUCLEOTIDE; PHOSPHORAMIDIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; ELECTRON SPIN RESONANCE; NUCLEOTIDE METABOLISM;

EID: 0035073306     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-12355     Document Type: Article

References (30)