Translocation and accumulation of exogeneous hapatitis B virus preS surface proteins in the cell nucleus

Journal of Cell Science

Volumn 114, Issue 6, 2001, Pages 1115-1123

  Cho, E W ^a   Park, J H ^a   Yoo, O J ^a   Kim, K L ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Energy independent translocation; Hepatitis B virus; PreS2 region

Indexed keywords

FLUORESCENT DYE; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; MEMBRANE PROTEIN; PRES PROTEIN; PROTEINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VITRONECTIN;

ARTICLE; CELL ENERGY; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; CELL STRAIN HEPG2; CELL TRANSPORT; CONTROLLED STUDY; CYTOPLASM; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; INTERNALIZATION; LIFE CYCLE; MEDIATOR; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; CELL MEMBRANE PERMEABILITY; CELL NUCLEUS; HELA CELLS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PEPTIDES; PROTEIN PRECURSORS; TUMOR CELLS, CULTURED;

DNA VIRUSES; HEPATITIS B VIRUS;

EID: 0035073042     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
2. Conformational and associative behaviors of the third helix of anttenapedia homeodomain in membrane-mimetic environments
3. Post-translational alterations in transmembrane topology of the hepatitis B virus large envelope protein
4. A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation
5. Expression of hepatitis B virus surface antigen gene in E. coli
6. Specific binding of the hepatitis B virus preS antigen to an EBV-transformed B-cell line
7. Production of monoclonal antibody to hepatitis B surface antigen and its application to radioimmunoassay
8. Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
9. Conformational and topological requirements of cell-permeable peptide function
10. Intercellular trafficking and protein delivery by a herpesvirus structural protein
11. Herpes simplex virus type 1 tegument protein VP22 induces the stabilization and hyperacetylation of microtubules
12. Tat-mediated delivery of heterologous proteins into cells
13. Infectious hepatitis B virus variant defective in pre-S2 protein expression in a chronic carrier
14. Expression of the terminal protein of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double stranded RNA
15. HIV-1 Gag proteins: Diverse functions in the virus life cycle
16. Hepadnaviridae and their replication
17. Studies on the attachment and penetration of hepatitis B virus
18. The role of the adenovirus protease on virus entry into cells
19. Hepatitis B virus nucleocapsid particle do not cross the hepatocyte nuclear membrane in transgenic mice
20. Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA
21. Characterization of essential domains for the functionality of the MHBst transcriptional activator and identification of a minimal MHBst activator
22. The hepatitis B virus large surface protein(LHBs) is a transcriptional activator
23. The PreS2 activators of the hepatitis B virus: Activators of tumour promoter pathways
24. In vitro model for the nuclear transport of the hepadnavirus genome
25. Phosphorylation-dependent binding of hepatitis B virus core particles to the nuclear pore complex
26. Visualization of antigens attached to cytoskeletal framework in animal cells: Colocalization of simian virus 40 Vp1 polypeptide and actin in TC7 cells
27. The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator
28. Hepatitis B virus preS1 functions as a transcriptional activation domain
29. The hepatitis B virus preS2/St transactivator utilizes AP-1 and other transcription factors for transactivation
30. Visualization of hepatitis B virus (HBV) surface protein binding to HepG2 cells
31. Role of the pre-S2 domain of the large envelope protein in hepatitis B virus assembly and infectivity
32. Protease-induced infectivity of hepatitis B virus for a human hepatoblastoma cell line
33. Hepatitis B surface antigen polypeptide(p31) with the receptor for polymerized human as well as chimpanzee albumins
34. Nucleocytoplasmic transport: The soluble phase
35. Solid phase synthesis
36. Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus
37. Novel cell permeable motif derived from the PreS2-domain of hepatitis-B virus surface antigens
38. A dramatic shift in the transmembrane topology of a viral envelope glycoprotein accompanies hepatitis B viral morphogenesis
39. Maltose binding protein (MBP) fusion proteins with low or no affinity to amylose resins can be single-step purified using a novel anti-MBP monoclonal antibody
40. The preS1 protein of hepatitis B virus is acylated at its amino terminus with myristic acid
41. Inhibitory activity of monoclonal antibody F35.25 on the interaction between hepatocytes (HepG2 cells) and preS1-specific ligands
42. Both pre-S1 and S domains of hepatitis B virus envelope proteins interact with the core particle
43. Identification of an attachment site for human liver plasma membranes on hepatitis B virus particles
44. Novel transmembrane topology of the hepatitis B virus envelope proteins
45. Adsorption and penetration of hepatitis B virus in a nonpermissive cell line
46. Molecular pathway involved in HIV-1-induced CNS pathology: Role of viral regulatory protein
47. Mapping of immunodominant B-cell epitopes and the human serum albumin-binding site in natural hepatitis B virus surface antigen of defined genosubtype
48. Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate
49. Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification
50. Morphogenetic and regulatory effects of mutation in the envelope proteins of an avian hepadnavirus
51. The middle hepatitis B virus envelope protein is not necessary for infectivity of hepatitis delta virus
52. Interaction of hepatitis B virus with hepatocytes: Mechanism and clinical relavance
53. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
54. The arginine-rich domain of hepatitis B virus precore and core proteins contains a signal for nuclear transport