Repeated endotoxin exposure induces interstitial fibrosis associated with enhanced gelatinase (MMP-2 and MMP-9) activity

Inflammation Research

Volumn 50, Issue 3, 2001, Pages 129-135

  Corbel, M ^a   Theret, N ^a   Caulet Maugendre, S ^b   Germain, N ^a   Lagente, V ^a   Clement, B ^a   Boichot, E ^a  

^a UNIVERSITÉ DE RENNES 1   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

Chronic inflammation; Collagen deposition; LPS; Lung; Metalloproteinase; Neutrophil

Indexed keywords

ENDOTOXIN; GELATINASE A; GELATINASE B; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; FIBROSING ALVEOLITIS; INFLAMMATORY DISEASE; LUNG FIBROSIS; LUNG INJURY; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; ZYMOGRAPHY;

ANIMALS; COLLAGEN; LIPOPOLYSACCHARIDES; LUNG; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; PULMONARY FIBROSIS;

EID: 0035071242     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050736     Document Type: Article

References (30)

1. Cytokines and pulmonary fibrosis
2. Extracellular matrix injury during lung inflammation
3. Proteolytic remodeling of extracellular matrix
4. Matrix metalloproteases and lung disease
5. Matrix metalloproteinases and lung injury
6. Mechanisms of neutrophil damage to human alveolar extracellular matrix: The role of serine and metalloproteases
7. Matrix metalloproteinase and elastase activities in LPS-induced acute lung injury in guinea pigs
8. Alveolar neutrophils in endotoxin-induced and bacteria-induced acute lung injury in rats
9. Functional and fine structural changes in isolated rat lungs challenged with endotoxin ex vivo and in vitro
10. Higher concentrations of matrix metalloproteinases in bronchoalveolar lavage fluid of patients with Adult Respiratory Distress Syndrome
11. Cell types involved in collagen and fibronectin production in normal and fibrotic human liver
12. Activation of matrix metalloproteinase -2 from hepatic stellate cells require interactions with hepatocytes
13. MMP-2 expression is associated with, but not sufficient for, malignant conversion of murine LTA cells
14. A simplified method for the analysis of hydroxyproline in biological tissues
15. Induction of 103 kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines
16. The effect of endotoxin on bleomycin-induced lung fibrosis in the rat
17. Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase
18. Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane
19. Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B
20. Migration of neutrophils across human pulmonary endothelial cells is not blocked by matrix metalloproteinase or serine protease inhibitors
21. Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis
22. Collagenase and fibronectin in bronchoalveolar lavage fluid in patients with sarcoidosis
23. Neutrophil collagenase in rheumatoid interstitial lung disease
24. Potential role of proteases in pulmonary fibrosis
25. Proteinase imbalance: Its role in lung disease
26. Localisation of matrix metalloproteinases-1, -2, and -9 and tissue inhibitor of metalloproteinase-2 in interstitial lung diseases
27. Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis
28. Production of collagenase and tissue inhibitor of metalloproteinases by fibroblasts derived from normal and fibrotic human lung
29. The family of matrix metalloproteinases
30. Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism