Column selection and method development for the determination of the enantiomeric purity of investigational non-nucleoside reverse transcriptase inhibitors

Chirality

Volumn 13, Issue 4, 2001, Pages 193-198

  Aubry, Anne Françoise ^a   Sebastian, Dolores S ^a   Williams, Reed C ^a   Boucher, Robert J ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Chiralpak AD; Chirobiotic V; Enantiomeric purity; HIV; NNRTI; Whelk O

Indexed keywords

6 CHLORO 4 (2 CYCLOPROPYLVINYL) 3,4 DIHYDRO 4 TRIFLUOROMETHYL 2(1H) QUINAZOLINONE; 6 CHLORO 4 CYCLOPROPYLETHYNYL 3,4 DIHYDRO 4 TRIFLUOROMETHYL 2(1H) QUINAZOLINONE; IL 854; RNA DIRECTED DNA POLYMERASE INHIBITOR; SQ 962; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG INDICATION; DRUG PURITY; DRUG STRUCTURE; ENANTIOMER; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PRIORITY JOURNAL; STEREOCHEMISTRY; VALIDATION PROCESS;

ANTI-HIV AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HIV INFECTIONS; HUMANS; QUINAZOLINES; QUINAZOLINONES; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE INHIBITORS; STEREOISOMERISM;

EID: 0035071187     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/chir.1019     Document Type: Article

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