Ecabet sodium inhibits the ability of Helicobacter pylori to induce neutrophil production of reactive oxygen species and interleukin-8

Journal of Gastroenterology

Volumn 36, Issue 3, 2001, Pages 153-157

  Shimoyama, T ^a   Fukuda, S ^a   Liu, Q ^a   Nakaji, S ^a   Munakata, A ^a   Sugawara, K ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Ecabet sodium; Helicobacter pylori; Neutrophil

Indexed keywords

12 SULFODEHYDROABIETIC ACID; ALPHA CHEMOKINE; ANTIULCER AGENT; BACTERIAL DNA; CHEMOKINE; DIMETHYL SULFOXIDE; ECABET; INTERLEUKIN 8; LUMINOL; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE; SODIUM CHLORIDE; SODIUM HYDROXIDE; ZYMOSAN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; CELL ACTIVITY; CELL CULTURE; CELL STIMULATION; CELL SUSPENSION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE ANALYSIS; GASTRITIS; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INCUBATION TIME; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; OXIDATIVE STRESS; PATHOGENICITY; PRIORITY JOURNAL; STOMACH MUCOSA LESION;

ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; CHEMILUMINESCENT MEASUREMENTS; DITERPENES; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERLEUKIN-8; NEUTROPHILS; REACTIVE OXYGEN SPECIES;

EID: 0035068294     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350170122     Document Type: Article

References (20)

1. Neutrophil activation by Helicobacter pylori
2. Incidence of Helicobacter pylori strains activating neutrophils in patients with peptic ulcer disease
3. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa
4. Induction of various cytokines and development of severe mucosal inflammation by cagA gene-positive. Helicobacter pylori strains
5. Interleukin-8 expression by human neutrophils activated by Helicobacter pylori soluble proteins
6. Chemokine mRNA expression in gastric mucosa is associated with Helicobacter pylori cagA positivity and severity of gastritis
7. Effects of a new anti-ulcer drug ecabet sodium (TA-2711) pepsin activity
8. Effects of ecabet sodium (TA-2711), a new antiulcer agent, on gastro-intestinal mucosal prostanoid production and morphology in rats
9. Minimum inhibitory concentration of various single agents and the effect of their combinations against Helicobacter pylori, as estimated by a fast and simple in vivo assay method
10. Ecabet sodium, a locally acting antiulcer drug, inhibits urease activity of Helicobacter pylori
11. Ecabet sodium eradicates Helicobacter pylori infection in gastric ulcer patients
12. Analysis and assessment of the capacity of neutrophils to produce reactive oxygen species in a 96-well microplate format using lucigenin and luminol-dependent chemiluminescence
13. A study of the fluorescence measurement using a 96-well microplate by a remodeled parallel luminescent measuring system
14. Oxidative DNA damage accumulation in gastric carcinogenesis
15. Further characterization of the neutrophil oxidative burst by flow cytometry
16. Ability of Helicobacter pylori to induce neutrophil oxidative burst is associated with gastric epithelial apoptosis
17. Mechanisms of disease: Chemokines-chemotactic cytokines that mediate inflammation
18. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cells
19. 2-forming NADPH-oxidase of phagocytes-nature, mechanisms of activation and function
20. Cell surface dynamics of neutrophils stimulated with phorbol esters or retinoids