The effect of hydrogen bonding on diffusion across model membranes: Consideration of the number of H-bonding groups

European Journal of Pharmaceutical Sciences

Volumn 13, Issue 2, 2001, Pages 135-141

  Du Plessis, Jeanetta ^a   Pugh, W John ^b   Judefeind, Anja ^b   Hadgraft, Jonathan ^c  

^a NORTH WEST UNIVERSITY   (South Africa)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Bio membranes; Diffusion; Hydrogen bonding; Phenols; Silicone; Skin

Indexed keywords

ADSORPTION; BIOLOGICAL MEMBRANES; DIFFUSION; HYDROGEN BONDS; PHENOLS; TOLUENE;

PERMEANTS;

SILICONES;

CATECHOL; HYDROQUINONE; OCTANOL; PHENOL; PHENOL DERIVATIVE; PHLOROGLUCINOL; PYROGALLOL; RESORCINOL; TOLUENE;

ARTICLE; DIFFUSION; DIFFUSION COEFFICIENT; DRUG SOLUBILITY; HYDROGEN BOND; INFRARED SPECTROSCOPY; MEMBRANE; MEMBRANE TRANSPORT; PARTITION COEFFICIENT; PRIORITY JOURNAL; SOLUBILITY; ULTRAVIOLET SPECTROPHOTOMETRY;

CATECHOLS; DIFFUSION; HYDROGEN BONDING; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; OCTANOLS; PHARMACOKINETICS; PHENOLS; SILICONES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 0035068143     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(00)00199-8     Document Type: Article

References (8)

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4. Epidermal permeability - penetrant structure relationships. 3. The effect of hydrogen-bonding interactions and molecular-size on diffusion across the stratum-corneum
5. Mechanism of percutaneous absorption. II. Transient diffusion and the relative importance of various routes of skin penetration
6. Epidermal Lipids
7. The determination of diffusion coefficients in semisolids by Fourier transform infrared (FT-IR) spectroscopy