Cisplatin-incorporated polymeric micelles eliminate nephrotoxicity, while maintaining antitumor activity

Japanese Journal of Cancer Research

Volumn 92, Issue 3, 2001, Pages 328-336

  Mizumura, Yasuo ^a   Matsumura, Yasuhiro ^a   Hamaguchi, Tetsuya ^a   Nishiyama, Nobuhiro ^b   Kataoka, Kazunori ^b   Kawaguchi, Takanori ^c   Hrushesky, William J M ^d   Moriyasu, Fuminori ^e   Kakizoe, Tadao ^a  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^d ALBANY MEDICAL COLLEGE   (United States)

^e TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Cisplatin; DDS; EPR effect; Nephrotoxicity; Polymeric micelles

Indexed keywords

ANTINEOPLASTIC AGENT; ASPARTIC ACID; CISPLATIN; COPOLYMER; LIGAND; MACROGOL; PLATINUM; POLYASPARTIC ACID; SODIUM CHLORIDE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; COLON CANCER; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG POTENCY; DRUG SOLUBILITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTESTINE INJURY; MALE; MICELLE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RODENT; STOMACH CANCER; TUMOR CELL LINE; TUMOR XENOGRAFT;

EID: 0035066765     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2001.tb01099.x     Document Type: Article

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