Impact of ACE I/D gene polymorphism on congenital renal malformations

Pediatric Nephrology

Volumn 16, Issue 4, 2001, Pages 356-361

  Hohenfellner, K ^a   Wingen, Anne Margret ^b   Nauroth, Oliver ^a   Wühl, Elke ^c   Mehls, Otto ^c   Schaefer, Franz ^c  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

ACE gene polymorphism; Congenital renal malformation; Progression of chronic renal failure

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; DNA;

ADOLESCENT; ADULT; ARTICLE; CAUCASIAN; CHILD; CHILDHOOD DISEASE; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; ENZYME ANALYSIS; FOLLOW UP; GENE DELETION; GENE INSERTION; GENETIC ANALYSIS; GENETIC DISORDER; GENOTYPE; GLOMERULOPATHY; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; KIDNEY DYSPLASIA; KIDNEY HYPOPLASIA; KIDNEY MALFORMATION; LINEAR SYSTEM; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; OBSTRUCTIVE UROPATHY; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEINURIA; REFLUX NEPHROPATHY; REGRESSION ANALYSIS; RISK ASSESSMENT; RISK FACTOR; SURVIVAL RATE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DISEASE PROGRESSION; DNA TRANSPOSABLE ELEMENTS; GENE DELETION; GENE FREQUENCY; GENOTYPE; HUMANS; KIDNEY; KIDNEY FAILURE, CHRONIC; MULTIVARIATE ANALYSIS; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 0035064001     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004670100567     Document Type: Article

References (30)

1. Epidemiology of chronic renal failure in children: A report from Sweden 1986-1994
2. Randomised multicentre study of a low-protein diet on the progression of chronic renal failure in children
3. Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy
4. The DD genotype of the ACE gene polymorphism is associated with progression of diabetic nephropathy to end stage renal failure in IDDM
5. Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy
6. Angiotensin converting enzyme gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathy
7. ACE gene polymorphism in childhood IgA nephropathy: Association with clinicopathologic findings
8. Angiotensin-converting enzyme gene polymorphism in patients with minimal-change nephrotic syndrome and focal segmental glomerulo-sclerosis
9. Genetic polymorphisms of the renin-angiotensin system and the outcome of focal segmental glomerulosclerosis in children
10. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels
11. Converting enzyme inhibition and renal tissue angiotensin II in the rat
12. The angiotensin type 2 receptor toxically inhibits angiotensin converting enzyme: Studies in AT2 null mutant mice
13. ACE I/D gene polymorphism predicts renal damage in congenital uropathies
14. Mistyping ACE heterozygotes
15. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ishemic heart disease
16. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents
17. Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men
18. Regulation of renal growth factors and clusterin by angiotensin AT1 receptors during neonatal ureteral obstruction
19. Association of the angiotensin I converting enzyme gene deletion polymorphism with early onset of ESRF in PKD1 adult polycystic kidney disease
20. Implications of certain genetic polymorphisms in scarring in vesicoureteric reflux: Importance of ACE polymorphism
21. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy
22. Effect of angiotensin-converting enzyme (ACE) gene polymorphism on progression of renal disease and the influence of ACE inhibition in IDDM patients Diabetes
23. Angiotensin II is involved in the progression of renal disease: Importance of non-hemodynamic mechanisms
24. Angiotensin-converting enzyme inhibition decreases growth factor expression in the neonatal rat kidney
25. Transforming growth factor 1 and renal injury following subtotal nephrectomy in the rat: Role of the renin-angiotensin system
26. Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats with obstructive nephropathy
27. Angiotensin II modulates cell growth-related events and synthesis of matrix proteins in renal interstitial fibrosis
28. Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy
29. Association of angiotensin I-converting enzyme gene poly-morphism with susceptibility to antiproteinuric effect of angiontensin I-converting enzyme inhibitors in patients with proteinuria
30. Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy