Plasma protein binding of 99mTc-labeled hydrazino nicotinamide derivatized polypeptides and peptides

Nuclear Medicine and Biology

Volumn 28, Issue 2, 2001, Pages 155-164

  Ono, Masahiro ^a   Arano, Yasushi ^b   Mukai, Takahiro ^a   Uehara, Tomoya ^b   Fujioka, Yasushi ^a   Ogawa, Kazuma ^a   Namba, Shinji ^a   Nakayama, Morio ^c   Saga, Tsuneo ^a   Konishi, Junji ^a   Horiuchi, Kazuko ^a   Yokoyama, Akira ^a   Saji, Hideo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

(poly)peptide; 99mTc; Coligand; HYNIC; Protein binding; Tricine

Indexed keywords

6 HYDRAZINOPYRIDINE 3 CARBOXYLIC ACID IMMUNOGLOBULIN F(AB) FRAGMENT CONJUGATE TC 99M; 6 HYDRAZINOPYRIDINE 3 CARBOXYLIC ACID IMMUNOGLOBULIN G CONJUGATE TC 99M; 6 HYDRAZINOPYRIDINE 3 CARBOXYLIC ACID VAPREOTIDE CONJUGATE TC 99M; IODINE 125; NICOTINAMIDE; NICOTINIC ACID; PLASMA PROTEIN; RADIOLIGAND; TRICINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONJUGATE; CONTROLLED STUDY; DERIVATIZATION; DRUG ELIMINATION; ISOTOPE LABELING; MALE; MOLECULAR SIZE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PLASMA CLEARANCE; PLASMA PROTEIN BINDING; PROTEIN LOCALIZATION; RADIOACTIVITY;

ANIMALS; BLOOD PROTEINS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; INDIUM RADIOISOTOPES; MALE; MICE; MICE, INBRED STRAINS; ORGANOTECHNETIUM COMPOUNDS; PENTETIC ACID; PROTEIN BINDING; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 0035062121     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(00)00200-6     Document Type: Article

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