Life and death in the JUNgle

Trends in Molecular Medicine

Volumn 7, Issue 4, 2001, Pages 141-142

  Weitzman, Jonathan B ^a  

^a Institut Pasteur   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN JUN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; KNOCKOUT MOUSE; MOLECULAR BIOLOGY; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0035060335     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1471-4914(01)01982-7     Document Type: Review

References (15)

1. Characterisation of junD: A new member of the jun proto-oncogene family
2. Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking JunB expression in the myeloid lineage
3. The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation
4. AP-1 function and regulation
5. c-Jun is essential for normal mouse development and hepatogenesis
6. A null mutation at the c-Jun locus causes embryonic lethality and retarded cell growth in culture
7. JunB is essential for mammalian placentation
8. Targeted disruption of the junD gene results in multiple defects in male reproductive function
9. Control of cell cycle progression by c-Jun is p53-dependent
10. Cellular transformation and malignancy induced by ras require c-Jun
11. JunD protects cells from p53-dependent senescence and apoptosis
12. Cell cycle-dependent variations in c-Jun and JunB phosphorylation: A role in the control of cyclin D1 expression
13. INK4a expression
14. Chronic myeloid leukemia
15. Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia