Combine-ARMS: A rapid and cost-effective protocol for molecular characterization of β-thalassemia in Malaysia

Genetic Testing

Volumn 5, Issue 1, 2001, Pages 17-22

  Tan, K L ^a   Tan, J A M A ^a   Wong, Y C ^a   Wee, Y C ^a   Thong, M K ^a   Yap, S F ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BETA THALASSEMIA; CLINICAL PROTOCOL; COST BENEFIT ANALYSIS; GENE MUTATION; HUMAN; MALAYSIA; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS;

ASIAN CONTINENTAL ANCESTRY GROUP; BETA-THALASSEMIA; CHINA; DNA MUTATIONAL ANALYSIS; ELECTROPHORESIS; FEMALE; HETEROZYGOTE; HUMANS; MALAYSIA; MUTATION; POLYMERASE CHAIN REACTION; PREGNANCY; PRENATAL DIAGNOSIS; SENSITIVITY AND SPECIFICITY;

MALAYA;

EID: 0035059012     PISSN: 10906576     EISSN: None     Source Type: Journal    
DOI: 10.1089/109065701750168626     Document Type: Article

References (14)

1. Screening for steroid sulfatase (STS) gene deletions via multiplex DNA amplification
2. Optimization of multiplex PCRs
3. Multiplex mutagenically separated PCR: Diagnosis of β-thalassemia and hemoglobin variants
4. Types of thalassaemia among patients attending a large University clinic in Kuala Lumpur, Malaysia
5. Treatment of β-thalassemia
6. Multiplex DNA deletion detection and exon sequencing of the hypoxanthine phosphoribosyltransferase gene in Lesch-Nyhan families
7. The spectrum of β-thalassaemia mutations in Taiwan: Identification of a novel frameshift mutation
8. Utility of the polymerase chain reaction (PCR) for prenatal diagnosis of genetic diseases
9. First-trimester fetal diagnosis for haemoglobinopathies: Report on 200 cases
10. Molecular characterization of β-thalassaemia in Singaporean Chinese: Application to prenatal diagnosis
11. The use of the Amplification Refractory Mutations System (ARMS) as an effective and economical tool for the prenatal diagnosis of β-thalassaemia in Malaysia
12. β-thalassaemia
13. Molecular heterogeneity of β-thalassaemia in Malaysia: A practical approach to diagnosis
14. Optimization strategies for the polymerase chain reaction