Activation of guanosine 5′-[γ-35S]thio-triphosphate binding through M1 muscarinic receptors in transfected Chinese hamster ovary cell membranes: 2. Testing the "two-states" model of receptor activation

Molecular Pharmacology

Volumn 59, Issue 4, 2001, Pages 886-893

  Waelbroeck, Magali ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; INOSITOL PHOSPHATE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR AGONIST; NUCLEOTIDE; PERTUSSIS TOXIN;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CATALYSIS; CELL MEMBRANE; CHO CELL; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG EFFECT; DRUG RECEPTOR BINDING; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SECRETION;

EID: 0035058763     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.4.886     Document Type: Article

References (41)

1. Effector pathway-dependant relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
2. Differential opioid agonist regulation of the mouse μ opioid receptor
3. Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: Evidence for agonist-specific trafficking of intracellular responses
4. 35S]GTPγS binding to rat cerebellar membranes correlates with agonist-induced decreases in GDP affinity
5. Mechanism of adenylate cyclase activation through the β-adrenergic receptor: Catecholamine-induced displacement of bound GDP by GTP
6. 50) of an enzymatic reaction
7. Inverse agonist activity of β-adrenergic antagonists
8. 35S]guanosine-5′-O-(3-thio)triphosphate binding mediated by cholinergic muscarinic receptors in membranes from Chinese hamster ovary cells and rat striatum using an anti-G protein scintillation proximity assay
9. Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes
10. 2 adrenoceptor
11. 2 adrenoceptor function. Evidence for protonation-dependent activation
12. The many faces of G protein signaling
13. Structural and functional aspects of G protein-coupled receptor oligomerization
14. 2AR through receptor dimerization
15. Morphine activates opioid receptors without causing their rapid internalization
16. 2 adrenergic receptor
17. s complex: Evidence for agonist-specific states
18. The role of receptor kinases and arrestins in G protein-coupled receptor regulation
19. 35S]GTP γ S binding mediated by human muscarinic m1-m4 receptors: Antagonist studies
20. Comparative effects of receptor inactivation, 17 β-estradiol and pertussis toxin on dopaminergic inhibition of prolactin secretion in vitro
21. 1b adrenergic receptor mutants display different phosphorylation and internalization features
22. Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor
23. G protein-coupled receptor kinases
24. 1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint
25. 1b-adrenergic receptor activation
26. Agonist-specific coupling of a cloned Drosophila octopamine/tyramine receptor to multiple second messenger systems
27. Antagonist-stimulated internalization of the G protein-coupled cholecystokinin receptor
28. 2-adrenergic receptor. Extending the ternary complex model
29. 2-adrenergic receptor
30. 1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
31. Requirement of specific intrahelical interactions for stabilizing the inactive conformation of glycoprotein hormone receptors
32. 2A receptor
33. s interactions: Evidence far multiple receptor conformations
34. 2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation
35. Evolving concepts of selective estrogen receptor action: From basic science to clinical applications
36. Differential signal transduction by five splice variants of the PACAP receptor
37. 1) receptors stimulate inositol phosphate synthesis in transfected CHO cells through interaction with different G proteins
38. 1 muscarinic receptors in transfected chinese hamster ovary cell membranes: 1. Mathematical analysis of catalytic G protein activation
39. The cubic ternary complex receptor-occupancy model. I. Model description
40. μ-opioid receptor phosphorylation, desensitization, and ligand efficacy
41. 2-adrenergic receptor