New drug combinations for the treatment of murine AIDS and macrophage protection

European Journal of Clinical Investigation

Volumn 31, Issue 3, 2001, Pages 248-252

  Fraternale, A ^a   Casabianca, A ^a   Tonelli, A ^a   Chiarantini, L ^a   Brandi, G ^a   Magnani, M ^a  

^a UNIVERSITY OF URBINO   (Italy)

Author keywords

AZT; Drug delivery system; Fludarabine; GSH; Murine retrovirus induced immunodeficiency (MAIDS)

Indexed keywords

ANTIRETROVIRUS AGENT; FLUDARABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL KILLING; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS REPLICATION;

ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; DRUG COMBINATIONS; FEMALE; MACROPHAGES; MICE; MICE, INBRED C57BL; MURINE ACQUIRED IMMUNODEFICIENCY SYNDROME; VIDARABINE; ZIDOVUDINE;

EID: 0035057381     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2362.2001.00806.x     Document Type: Article

References (11)

1. Latent infection of CD4+ T cells provides a mechanism for life long persistence of HIV-1, even in patients on effective combination therapy
2. Glutathione inhibits replication and expression of viral proteins in cultured cells infected with Sendai virus
3. Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine
4. Inhibition of murine AIDS by reduced glutathione
5. Targeting antiretroviral nucleotide analogues in phosphorylated form to macrophages: In vitro and in vivo studies
6. Fludarabine phosphate: A synthetic purine antimetabolite with significant activity against lymphoid malignancies
7. Inhibition of murine AIDS by alternate administration of Azidothymidine and Fludarabine monophosphate
8. New treatment protocol including lympholitic and antiretroviral drugs to inhibit routine AIDS
9. Role of macrophage protection in the development of murine AIDS
10. Competitive PCR for quantification of BM5d proviral DNA in mice with AIDS
11. In vitro and in vivo toxicity of 2′,3′-dideoxycytidine in mice