Rate-dependent electrical, contractile and restitution properties of isolated left ventricular myocytes in guinea-pig hypertrophy

Acta Physiologica Scandinavica

Volumn 171, Issue 1, 2001, Pages 17-28

  Davey, P ^a,b   Bryant, S ^a,b   Hart, G ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b Clinical Department   (United Kingdom)

Author keywords

Electrical and mechanical restitution; Force frequency relationship; Guinea pig; Hypertrophy; Membrane potential; Myocyte

Indexed keywords

ADRENERGIC STIMULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; FEMALE; GUINEA PIG; HEART DEATH; HEART LEFT VENTRICLE CONTRACTILITY; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE POTENTIAL; HEART MUSCLE RELAXATION; HEART RATE; HEART REPOLARIZATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0035054591     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.2001.00779.x     Document Type: Article

References (41)

1. The interval-strength relation of cardiac muscle: Past, present and future
2. Excitation and contraction in atrial and ventricular myocardium of the guinea-pig
3. Cellular basis of contractile derangements of hypertrophied feline ventricular myocytes
4. Sarcoplasmic reticulum-related changes in cvtosolic calcium in pressure-overload-induced feline LV hypertrophy
5. Ambulatory sudden cardiac death: Mechanisms of production of fatal arrhythmia on the basis of data from 157 cases
6. A study of the factors responsible for rate-dependent shortening of the action potential in mammalian ventricular muscle
7. Analysis of the effects of changes in rate and rhythm upon electrical activity in the heart
8. New insights into cardiac excitationcontraction coupling in normal and hypertension/failure animal models
9. Mechanical restitution in isolated mammalian myocardium: Species differences and underling mechanisms
10. Mechanical restitution of isolated human ventricular myocardium subjected to in vivo pressure and volume overload
11. Reduced contraction and altered frequency response of isolated ventricular myocytes from patients with heart failure
12. Optical methods to evaluate the contractile function of unloaded isolated cardiac myocytes
13. Hypertensive-diabetic cardiomyopathy in rats
14. Intracellular calcium transients underlying the short term force interval relationship in ferret ventricular myocardium
15. Altered calcium handling in experimental pressure overload in the ferret
16. Sarcoplasmic reticulum calcium mobilization in right ventricular pressure-overload hypertrophy in the ferret: Relationships to diastolic dysfunction and a negative treppe
17. The role of the Na(+)-Ca2+ exchanger in the rate-dependent increase in contraction in guinea-pig ventricular myocytes
18. Cellular electrophysiology in cardiac hypertrophy and failure
19. The role of Na(+)-Ca2+ exchange current in electrical restitution in ferret ventricular cells
20. Post-extrasystolic potentiation and its decay
21. Alteration of Ca2+ release channel function in sarcoplasmic reticulum of pressure-overload-induced hypertrophic rat heart
22. Mechanisms contributing to pulsus alternans in pressure-overload cardiac hypertrophy
23. Major alterations in relaxation during cardiac hypertrophy induced by aortic stenosis in the guinea-pig
24. Quantitative aspects of cellular calcium regulation during post-rest stimulation in cardiac muscle: Implications for steady state conditions
25. Electrical restitution in diseased human ventricular myocardium
26. Electrophysiological characteristics of single myocytes isolated from hypertrophied guinea-pig hearts
27. Effect of duration of depolarisation on contraction of normal and hypertrophied feline ventricular myocytes
28. Post-extrasystolic potentiation and the force-frequency relationship: Differential augmentation of myocardial contractility in wording myocardium from patients with end stage heart failure
29. The effects of compensated cardiac hypertrophy on dihydropyridlne and ryanodine receptors in rat, ferret and guinea-pig hearts
30. Electrophysiological studies of Syrian hamster hereditary cardiomyopathy
31. Membrane current changes in left ventricular myocytes isolated from guinea-pigs after abdominal aortic coarctation
32. Altered calcium handling at normal contractility in hypertrophied rat heart
33. Sodium/calcium exchanger in heart muscle: Molecular biology, cellular function, and its special role in excitationcontraction coupling
34. Relationships between beat-to-beat interval and the strength of contraction in the healthy and diseased human heart
35. Review: Relation between beat interval and force of the heartbeat and its clinical implications
36. Involvement of the sarcoplasmic reticulum calcium pump in myocardial contractile dysfunction: Comparison between chronic pressure-overload and stunning
37. Decreased sodiumpotassium pump activity in isolated hypertrophied feline ventricular myocytes
38. The effects of changes to action potential duration on the calcium content of the sarcoplasmic reticulum in isolated guinea-pig ventricular myocytes
39. Diminished effect of cAMP on Ca2+ accumulation in skinned fibers of hypertrophied rat heart
40. Calcium current restitution in mammalian ventricular myocytes is modulated by intra-cellular calcium
41. Restitution of contractility in single ventricular myocytes of guinea pig heart