Inhibition of aldosterone production in rat adrenal mitochondria by 18-ethynyl-11-deoxycorticosterone: A simple model for kinetic interpretation of mechanism-based inhibitors

Journal of Biochemistry

Volumn 129, Issue 3, 2001, Pages 383-390

  Matkovic, Laura ^a   Gomez Sanchez, Celso E ^b,c   Cozza, Eduardo N ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

18 ethynyl 11 deoxycorticosterone; Adrenal gland; Aldosterone; Mechanism based inhibitors; Suicide inhibitors

Indexed keywords

18 ETHYNYL 11 DEOXYCORTICOSTERONE; ALDOSTERONE; DEOXYCORTICOSTERONE; SUICIDE SUBSTRATE; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; MATHEMATICAL MODEL; MITOCHONDRION; NONHUMAN; RAT;

ANIMALIA;

EID: 0035054002     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002868     Document Type: Article

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