Genetic polymorphisms of thiopurine S-methyltransferase and 6-mercaptopurine toxicity in Japanese children with acute lymphoblastic leukaemia

Pharmacogenetics

Volumn 11, Issue 3, 2001, Pages 269-273

  Ando, M ^a   Ando, Y ^a   Hasegawa, Y ^a   Sekido, Y ^a   Shimokata, K ^a   Horibe, K ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ethnic difference; Heterozygote; Phamacogenetics; Thiopurine S methyltransferase

Indexed keywords

DRUG METABOLIZING ENZYME; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CHILD; CHILDHOOD LEUKEMIA; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INFANT; JAPAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

6-MERCAPTOPURINE; ADOLESCENT; ANTIMETABOLITES, ANTINEOPLASTIC; BONE MARROW; CHILD; CHILD, PRESCHOOL; FEMALE; HETEROZYGOTE; HUMANS; JAPAN; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; METHYLTRANSFERASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 0035052283     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200104000-00011     Document Type: Article

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