Kasabach-Merritt syndrome: Pathogenesis and management

British Journal of Haematology

Volumn 112, Issue 4, 2001, Pages 851-862

  Hall, Georgina W ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Consumptive coagulopathy; Haemangioma; Kasabach Merritt

Indexed keywords

ALPHA INTERFERON; CYCLOPHOSPHAMIDE; DACTINOMYCIN; ETOPOSIDE; IMMUNOGLOBULIN G; PREDNISOLONE; PROSTACYCLIN; TRANEXAMIC ACID; VINCRISTINE;

ARTIFICIAL EMBOLISM; CLINICAL FEATURE; DIAGNOSTIC APPROACH ROUTE; DISEASE ASSOCIATION; KASABACH MERRITT SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SPLENECTOMY; TREATMENT OUTCOME;

ANTICOAGULANTS; ANTIFIBRINOLYTIC AGENTS; CHILD; CHILD, PRESCHOOL; EMBOLIZATION, THERAPEUTIC; FEMALE; GLUCOCORTICOIDS; HEMANGIOMA, CAPILLARY; HUMANS; INFANT; INFANT, NEWBORN; INTERFERON-ALPHA; LASER SURGERY; MALE; PLATELET AGGREGATION INHIBITORS; PURPURA, THROMBOCYTOPENIC; SYNDROME;

EID: 0035052152     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02453.x     Document Type: Review

References (89)

1. Severe hemorrhage complicating the Klippel-Trenaunay-Weber syndrome
2. Disseminated intravascular coagulation: Diagnosis and treatment
3. Spastic diplegia as a complication of interferon alfa-2a treatment of hemangiomas of infancy
4. Treatment of proliferative haemangiomata with the 585nm pulsed dye laser
5. Perinatal subglottic and hepatic hemangiomas as potential emergencies: Effect of radiotherapy
6. Reversal of coagulopathy in Kasabach - Merritt syndrome with tranexamic acid
7. Role of low-dose radiotherapy in the multimodal treatment of Kasabach-Merritt syndrome
8. Vertebral haemangioma presenting as Kasabach-Merritt syndrome
9. Successful multimodal therapy for kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon: Case report and review of the literature
10. Giant hemangioma with thrombocytopenia - Radioisotope demonstration of platelet sequestration
11. Diffuse infantile haemangiomatosis: Clinicopathological features and management problems in five fatal cases
12. Kasabach-Merritt syndrome with bone involvement: The pseudomalignant sign of Gorham
13. Successful treatment of infantile hemangiomas with Interferon-a-2b
14. Prenatal diagnosis of Klippel-Trenaunay-Weber syndrome as a cause for in utero heart failure and severe postnatal sequelae
15. Management of disseminated intravascular coagulation
16. Thalidomide is an inhibitor of angiogenesis
17. Successful treatment of Kasabach-Merritt syndrome with pentoxifylline
18. Importance of bFGF ('basic fibroblast growth factor') for diagnosis and treatment of hemangiomas
19. Successful treatment of Kasabach-Merritt syndrome with prednisone and epsilonaminocaproic acid
20. Hemangiomas in children
21. Current perspectives in the treatment of thrombotic disorders
22. Toxicity profile of interferon a2b in children: A prospective evaluation
23. Kasabach-Merritt syndrome
24. Management of alarming hemangiomas in infancy: A review of 25 cases
25. Infants with Kasabach-Merritt syndrome do not have 'true' hemangiomas
26. Residual lesions after Kasabach-Merritt phenomenon in 41 patients
27. Kasabach-Merritt syndrome in infants
28. Interferon alfa-2a therapy for life-threatening hemangioma of infancy
29. Kaposiform haemangioendothelioma associated with Kasabach-Merritt syndrome
30. Congenital cutaneous multifocal kaposiform hemangioendothelioma
31. Multiple hemangiomata associated with thrombocytopenia: Remarks on the pathogenesis of the thrombocytopenia in this syndrome
32. Tranexamic acid in the treatment of Kasabach-Merritt syndrome in infants
33. Are Angiostatin and Endostatin cures for cancer?
34. Successful management of an infant with a giant hemangioma of the retroperitoneum and Kasabach-Merritt syndrome with alpha-interferon
35. Chronic consumption coagulopathy due to an occult splenic haemangioma: Kasabach-Merritt syndrome
36. Successful transcutaneous arterial embolization of a giant hemangioma associated with high-output cardiac failure and Kasabach-Merritt syndrome in a neonate: A case report
37. Kasabach-Merritt syndrome-associated kaposiform hemangioendothelioma successfully treated with cyclophosphamide, vincristine, and actinomycin D
38. Capillary hemangioma with extensive purpura. Report of a case
39. Use of aspirin and dipyridamole in children with platelet trapping syndromes
40. Interferon alpha-2a therapy for disseminated intravascular coagulation in a patient with blue rubber bleb nevus syndrome. A case report
41. Hepatic hemangioma
42. Human angiostatin inhibits murine hemangioendothelioma tumor growth in vivo
43. Kasabach-Merritt syndrome: Therapeutic considerations
44. Pregnancy associated with giant hemangiomata, thrombocytopenia, and fibrinogenopenia (Kasabach-Merritt syndrome). Report of a case
45. Treatment of a giant haemangioma of the liver with Kasabach-Merritt syndrome by orthotopic liver transplant a case report
46. Diffuse neonatal haemangiomatosis: New views on diagnostic criteria and prognosis
47. The use of interferon alfa-2a for life-threatening hemangiomas
48. Pentoxifylline in the treatment of children with new-onset type I diabetes mellitus
49. Kasabach-Merritt syndrome
50. MRI of intralesional hemolysis in focal nodular hyperplasia of the liver
51. Thalidomide in children undergoing bone marrow tranplantation: Series at a single institution and review of literature
52. Long term follow-up of a case of Kasabach-Merritt syndrome successfully treated with radiotherapy and corticosteroids
53. Outcome of radiation therapy for patients with Kasabach-Merritt syndrome
54. A case of Kasabach-Merrit syndrome complicated with DIC treated effectively by long term oral administration of warfarin
55. The infant with a vascular tumor
56. Hemangiomas and vascular malformations in infants and children: A classification based on endothelial characteristics
57. Kasabach-Merritt syndrome associated with angioblastoma
58. Kasabach-Merritt coagulopathy complicating Klippel-Trenaunay-Weber syndrome in pregnancy
59. Hemangioma with Kaposi's sarcoma-like features: Report of two cases
60. High doses of methylprednisolone for Kasabach-Merritt syndrome
61. Megadose methylprednisolone for Kasabach-Merritt syndrome
62. Megadose methylprednisolone for Kasabach-Merritt syndrome
63. Treatment of life-threatening hemangiomas with vincristine
64. Kasabach-Merritt syndrome exacerbated by platelet transfusion
65. Update on hemangiomas and vascular malformations
66. Prenatal diagnosis of an extensive haemangioma of the fetal leg: A case report
67. Klippel-Trenaunay syndrome: Clinical features, complications and management in children
68. Kasabach-Merrit syndrome in infants
69. Thrombocytopenic coagulopathy (Kasabach-Merritt phenomenon) is associated with Kaposiform hemangioendothelioma and not with common infantile hemangioma
70. Embolization therapy in the management of infantile hemangioma with Kasabach Merritt syndrome
71. Anaemia, thrombocytopenia and coagulopathy due to occult diffuse infantile haemangiomatosis of spleen and pancreas
72. Kasabach-Merritt syndrome: Identification of platelet trapping in a tufted angioma by immunohistochemistry technique using monoclonal antibody to CD61
73. Hemangiomas of infancy complicated by thrombocytopenia
74. Acute onset of coagulopathy in a patient with Kasabach-Merritt syndrome following transurethral resection of bladder tumor
75. Kasabach-Merritt syndrome: Treatment with epsilon-aminocaproic acid and assessment by indium 111 platelet scintigraphy
76. Subglottic hemangioma: Ten years' experience with the carbon dioxide laser
77. Kasabach-Merritt syndrome in two successive pregnancies
78. Kasabach-Merritt syndrome treated by therapeutic embolization with polyvinyl alcohol
79. Kasabach-Merritt syndrome: A case review
80. Current status of antiangiogenic factors
81. Kasabach-Merritt syndrome in children
82. Serious childhood angiomas: Unsuccessful alpha-2b interferon treatment. A report of four cases
83. Veno-occlusive disease of the liver in right sided Wilm's tumours
84. Neonatal Kasabach-Merritt syndrome healed by complete surgical excision of the angioma
85. Treatment of the Kasabach-Merritt syndrome with pegylated recombinant human megakaryocyte growth and development factor in mice: Elevated platelet counts, prolonged survival, and tumor growth inhibition
86. Liver tumors in neonates and very young infants: Diagnostic pitfalls and therapeutic problems
87. Intratumoral consumption of indium-111 labeled platelets in a patient with hemangiomatosis and intravascular coagulation (Kasabach-Merritt syndrome)
88. Interferon a2a therapy in haemangioma of infancy: Spastic diplegia as a severe complaint
89. Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis