Prediction of In-vivo efficacy by In-vitro early bactericidal activity with oral β-lactams, in a dose-ranging immunocompetent mouse sepsis model, using strains of Streptococcus pneumoniae with decreasing susceptibilities to penicillin

Journal of Chemotherapy

Volumn 13, Issue 2, 2001, Pages 118-125

  Perez Trallero E ^a   Alkorta, M ^a   Gimenez M J ^a   Vicente, D ^a   Aguilar, L ^a  

^a HOSPITAL DONOSTIA   (Spain)

Author keywords

Amoxicillin; Animal model; Oral cephalosporins; Streptococcus pneumoniae

Indexed keywords

AMOXICILLIN; BETA LACTAM ANTIBIOTIC; CEFPODOXIME; CEFPODOXIME PROXETIL; CEFUROXIME; CEFUROXIME AXETIL; CEPHALOSPORIN DERIVATIVE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERICIDAL ACTIVITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFICACY; FEMALE; IMMUNOCOMPETENCE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; SEPSIS; STRAIN DIFFERENCE; STREPTOCOCCUS PNEUMONIAE; SURVIVAL;

EID: 0035052125     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2001.13.2.118     Document Type: Article

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