A flexible design for multiple armed screening trials

Statistics in Medicine

Volumn 20, Issue 7, 2001, Pages 1051-1060

  Sargent, Daniel J ^a   Goldberg, Richard M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PLACEBO;

ARTICLE; CANCER CHEMOTHERAPY; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DECISION MAKING; DRUG ACTIVITY; DRUG EFFICACY; HUMAN; MATHEMATICAL ANALYSIS; METHODOLOGY; PATIENT CARE; PHASE 2 CLINICAL TRIAL; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; SCREENING; STATISTICAL ANALYSIS; TREATMENT OUTCOME;

BIAS (EPIDEMIOLOGY); CLINICAL TRIALS, PHASE II; CLINICAL TRIALS, PHASE III; HUMANS; MODELS, STATISTICAL; RANDOMIZED CONTROLLED TRIALS; TREATMENT OUTCOME;

EID: 0035050901     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/sim.704     Document Type: Article

References (8)

1. Randomized phase II clinical trials
2. Two-stage selection and testing designs for comparative clinical trials
3. A two-stage design for choosing among several experimental treatments and a control in clinical trials
4. False positive rates of randomized phase II designs
5. Discussion of paper by Spiegelhalter, Freedman, and Parmar
6. Discussion of paper by Spiegelhalter, Freedman, and Parmar
7. Bayesian sequential monitoring designs for single arm clinical trials with multiple outcomes