Increased calcium influx is responsible for the sustained mechanical tone in colon from dystrophic (mdx) mice

Gastroenterology

Volumn 120, Issue 6, 2001, Pages 1430-1437

  Mulè, Flavia ^a   Serio, Rosa ^b  

^a UNIVERSITY OF CALABRIA   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; CALCIUM CHANNEL L TYPE; CYCLOPIAZONIC ACID; NIFEDIPINE; PINAVERIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; COLON; CONTROLLED STUDY; DISEASE ASSOCIATION; DUCHENNE MUSCULAR DYSTROPHY; INTESTINE CONTRACTION; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE TONE;

EID: 0035048896     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(01)81483-9     Document Type: Article

References (46)

1. Dystrophin: The protein product of the Duchenne muscular dystrophy locus
2. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein
3. The Duchenne muscular dystrophy gene product is localised in sarcolemma of human skeletal muscle
4. Possible systemic smooth muscle layer dysfunction due to deficiency of dystrophin in Duchenne muscular dystrophy
5. Dystrophin protects the sarcolemma from stresses developed during muscle contraction
6. Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy
7. Calcium homeostasis in dystrophic muscle
8. Calcium-mediated mechanisms in chemically induced cell death
9. Total ion content of skeletal and cardiac muscle in the mdx mouse dystrophy: Calcium is elevated at all ages
10. Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice
11. 2+ levels in myotubes grown from skeletal muscle of dystrophic (mdx) and normal mice
12. A critical evaluation of resting intracellular free calcium regulation in dystrophic mdx muscle
13. Increased calcium influx in dystrophic muscle
14. Increased calcium entry into dystrophin- ↑ deficient muscle fibres of MDX and ADR-MDX mice is reduced by ion channel blockers
15. Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin
16. Calcium entry through stretch-inactivated ion channels in mdx myotubes
17. Regulation of cytosolic calcium in skeletal muscle cells of the mdx mouse under conditions of stress
18. Dystrophin and disease
19. 2+ concentrations are not elevated in resting cultured muscle from Duchenne (DMD) patients and in MDX mouse muscle fibres
20. Critical evaluation of cytosolic calcium determination in resting muscle fibres from normal and dystrophic (mdx) mice
21. Membrane potential, resting calcium and calcium transients in isolated muscle fibres from normal and dystrophic mice
22. The subcellular distribution of dystrophin in mouse skeletal, cardiac, and smooth muscle
23. Phenotype of dystrophinopathy in old mdx mice
24. Gastric hypornotility in Duchenne's muscular dystrophy
25. Chronic intestinal pseudo-obstruction as a complication of Duchenne's muscular dystrophy
26. Skeletal, cardiac, and smooth muscle failure in Duchenne muscular dystrophy
27. Analysis of peristaltic reflex in young mdx dystrophic mice
28. Mechanical activity of small and large intestine in normal and mdx mice: A comparative analysis
29. Nitric oxide regenerates the normal colonic peristaltic activity in mdx dystrophic mouse
30. 2+-ATPase of sarcoplasmic reticulum
31. Functional alterations in the aorta of the spontaneously hypertensive rat: Pharmacological assessment with cyclopiazonic acid
32. Membrane abnormalities and Ca homeostasis in muscles of the mdx mouse, an animal model of the Duchenne muscular dystrophy: A review
33. Lack of dystrophin but normal calcium homeostasis in the smooth muscle from dystrophic mdx mice
34. Site-dependent pathological differences in smooth muscle and skeletal muscles of the adult mdx mouse
35. Decreased osmotic stability of dystrophinless muscle from the mdx mouse
36. Altered electrical activity in colonic smooth muscle cells from dystrophic (mdx) mice
37. Effects of pinaverium on voltage-activated calcium channel currents of single smooth muscle cells isolated from the longitudinal muscle of the rabbit jejunum
38. Role of intracellular calcium in promoting muscle damage: A strategy for controlling the dystrophic condition
39. The sarcoplasmic reticulum calcium pump is functionally altered in dystrophic muscle
40. Calcium regulation in muscle diseases; the influence of innervation and activity
41. 2+-ATPase inhibitor, on contractile responses in skinned ileal smooth muscle
42. Use of calcium pump inhibitors in the study of calcium regulation in smooth muscle
43. Calcium release from intracellular stores and excitation-contraction coupling in intestinal smooth muscle
44. 2+-ATPase in sarcoplasmic reticulum, increases excitability in ileal smooth muscle
45. 2+ stores in ileal smooth muscle of the rat
46. Calcium source diversity in canine lower esophageal sphincter muscle