Rapid production of recombinant allergens in Nicotiana benthamiana and their impact on diagnosis and therapy

International Archives of Allergy and Immunology

Volumn 124, Issue 1-3, 2001, Pages 48-50

  Breiteneder, Heimo ^a   Krebitz, M ^a   Wiedermann, U ^a   Wagner, B ^a   Essl, D ^b   Steinkellner, H ^b   Turpen, T H ^c   Ebner, C ^a   Buck, D ^d   Niggemann, B ^d   Scheiner, O ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^c Large Scale Biology Corporation   (United States)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Allergens, recombinant; Bet v 1; Hev b 1; Hev b 3; Nicotiana benthamiana; Tobacco mosaic virus

Indexed keywords

IMMUNOGLOBULIN E; POLLEN ANTIGEN; VIRUS VECTOR;

ALLERGY; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; IMMUNOGENICITY; MOUSE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; TOBACCO; TOBACCO MOSAIC VIRUS;

ALLERGENS; ANIMALS; DERMATITIS, ATOPIC; GENETIC VECTORS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNOGLOBULIN E; MICE; MICE, INBRED BALB C; PLANT PROTEINS; PLANTS, TOXIC; RECOMBINANT PROTEINS; TOBACCO; TOBACCO MOSAIC VIRUS;

EID: 0035048364     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053665     Document Type: Conference Paper

References (5)

1. Expression of the green fluorescent protein-encoding gene from a tobacco mosaic virus-based vector
2. Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single chain Fv epitopes in tobacco plants
3. Heterologous sequences greatly affect foreign gene expression in tobacco mosaic virus-based vectors
4. Purification and characterization of recombinant Bet v I, the major birch pollen allergen. Immunological equivalence to natural Bet v I
5. Effects of adjuvants on the immune response to allergens in a murine model of allergen-inhalation: Cholera toxin induces a Th1 like immune response to Bet v 1, the major birch pollen allergen