A pharmacokinetic and pharmacodynamic comparison of desmopressin administered as whole, chewed and crushed tablets, and as an oral solution

Journal of Urology

Volumn 165, Issue 5 I, 2001, Pages 1446-1451

  Argenti, Domenick ^a   Ireland, Denise ^a   Heald, Donald L ^a  

^a SANOFI   (France)

Author keywords

Bladder; Desmopressin; Pharmacokinetics; Therapeutic equivalency; Urination disorders

Indexed keywords

DESMOPRESSIN;

ADULT; ANTIDIURESIS; AREA UNDER THE CURVE; ARTICLE; CHEWABLE TABLET; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; HUMAN; HUMAN EXPERIMENT; MALE; MICTURITION DISORDER; NORMAL HUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; URINE OSMOLALITY; URINE VOLUME;

EID: 0035047072     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0022-5347(05)66325-2     Document Type: Article

References (13)

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2. Management of nocturnal enuresis with a vasopressin analogue
3. Antidiuretic effect and pharmacokinetics of oral 1-desamino-8-D-arginine vasopressin. 1. Studies in adults and children
4. Oral desmopressin for nocturnal polyuria in elderly subjects: A double-blind, placebo-controlled randomized exploratory study
5. Oral desmopressin: A randomized double-blind placebo controlled study of effectiveness in children with primary nocturnal enuresis
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7. Desmopressin in the treatment of nocturnal polyuria in the male
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9. Oral desmopressin treatment of central diabetes insipidus in children
10. Peroral drug administration to children - Are there any problems?
11. DDAVP tablets
12. The duration of antidiuretic response of two desmopressin nasal sprays