C-type natriuretic peptide-induced vasodilation is dependent on hyperpolarization in human forearm resistance vessels

Hypertension

Volumn 37, Issue 4, 2001, Pages 1179-1183

  Honing, Marina L H ^a,b,c,d   Smits, Paul ^a,b,c,d   Morrison, Paul J ^a,b,c,d   Burnett Jr, John C ^a,b,c,d   Rabelink, Ton J ^a,b,c,d  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Kendle   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d MAYO CLINIC   (United States)

Author keywords

Endopeptidase; Hyperpolarizing factor; Natriuretic peptides; Nitric oxide; Tetraethylammonium chloride

Indexed keywords

ACETYLSALICYLIC ACID; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; MEMBRANE METALLOENDOPEPTIDASE; N(G) METHYLARGININE; NATRIURETIC PEPTIDE TYPE C; NITRIC OXIDE; POTASSIUM CHANNEL; PROSTACYCLIN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; TETRYLAMMONIUM CHLORIDE; THIORPHAN;

ADULT; ARTICLE; BLOOD VESSEL TONE; CHANNEL GATING; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; FOREARM BLOOD FLOW; HUMAN; HUMAN EXPERIMENT; HYPERPOLARIZATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RESISTANCE BLOOD VESSEL; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 0035045968     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.37.4.1179     Document Type: Article

References (26)

1. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-β: Possible existence of "vascular natriuretic peptide system"
2. Action of C-type natriuretic peptide in isolated canine arteries and veins
3. Mechanisms of natriuretic-peptide-induced growth inhibition of vascular smooth muscle cells
4. Endothelium-independent relaxation and hyperpolarization to C-type natriuretic peptide in porcine coronary arteries
5. Presence of C-type natriuretic peptide in cultured human endothelial cells and plasma
6. Vasodilator actions of bradykinin are partially mediated through release of C-type natriuretic peptide
7. Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide
8. Vascular actions of C-type natriuretic peptide in isolated porcine coronary arteries and coronary vascular smooth muscle cells
9. Characterization of atrial natriuretic peptide in urine from rats treated with a neutral endopeptidase inhibitor
10. Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11
11. Neutral endopeptidase 24.11: Structure, inhibition, and experimental and clinical pharmacology
12. Measuring forearm bloodflow and interpreting the responses to drugs and mediators
13. Aspirin causes short-lived inhibition of bradykinin-stimulated prostacyclin production in man
14. Block of calcium-activated potassium channels in mammalian arterial myocytes by tetraethylammonium ions
15. Thiazide-induced vasodilation in humans is mediated by potassium channel activation
16. Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo
17. In vivo characterization of vasodilating muscarinic-receptor subtypes in humans
18. C-type natriuretic peptide: A selective cardiovascular peptide
19. Biological actions and pharmacokinetics of C-type natriuretic peptide in conscious sheep
20. Low-dose C-type natriuretic peptide does not affect cardiac and renal function in humans
21. Neutral endopeptidase regulates C-type natriuretic peptide metabolism but does not potentiate its bioactivity in vivo
22. Shear stress induces expression of CNP gene in human endothelial cells
23. Shear stress augments expression of C-type natriuretic peptide and adrenomedullin
24. Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor
25. CNP is present in canine renal tubular cells and secreted by cultured opossum kidney cells
26. Bradykinin blocks angiotensin II-induced hypertrophy in the presence of endothelial cells