The acute effects of zolpidem compared to diazepam and lorazepam using radiotelemetry

Neuropharmacology

Volumn 40, Issue 5, 2001, Pages 717-721

  Elliot, E E ^a,b   White, J M ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Diazepam; Lorazepam; Muscle relaxation; Radiotelemetry; Zolpidem

Indexed keywords

BENZODIAZEPINE DERIVATIVE; DIAZEPAM; IMIDAZOPYRIDINE DERIVATIVE; LORAZEPAM; ZOLPIDEM;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ELECTROMYOGRAPHY; HYPOTHERMIA; LOCOMOTION; MALE; MUSCLE RELAXATION; NONHUMAN; PRIORITY JOURNAL; RAT; TELEMETRY;

ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; DIAZEPAM; ELECTROMYOGRAPHY; HYPNOTICS AND SEDATIVES; LORAZEPAM; MALE; MOTOR ACTIVITY; PYRIDINES; RATS; RATS, WISTAR; TELEMETRY;

EID: 0035045597     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00196-9     Document Type: Article

References (20)

1. Pharmacological profile of the imidazopyridine zolpidem at benzodiazepine receptors and electrocorticogram in rats
2. Comparative autoradiographic distribution of central omega (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem
3. Use of telemetry to record body temperature and activity in mice
4. Evidence for central benzodiazepine receptor heterogeneity from behavior tests
5. Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects
6. Distribution of [3H]zolpidem binding sites in relation to messenger RNA encoding the alpha 1, beta 2 and gamma 2 subunits of GABAA receptors in rat brain
7. Benzodiazepine concentrations in brain directly reflect receptor occupancy: Studies of diazepam, lorazepam, and oxazepam
8. New evidence that the pharmacological effects of benzodiazepine receptor ligands can be associated with activities at different BZ (omega) receptor subtypes
9. Diazepam: Kinetic profiles in various brain areas, plasma and erythrocytes after chronic administration in the rat
10. An update on thermosensitive neurons in the brain: From cellular biology to thermal and non-thermal homeostatic functions
11. Temperature-sensitive neurons in the hypothalamus: A new hypothesis that they act as thermostats, not as transducers
12. Zolpidem. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential
13. Function and pharmacology of multiple GABAA receptor subunits
14. The interaction between zolpidem and beta-CMC: A clue to the identification of receptor sites involved in the sedative effect of zolpidem
15. Type I and type II GABAA-benzodiazepine receptors produced in transfected cells
16. Recent developments in the behavioral pharmacology of benzodiazepine (omega) receptors: Evidence for the functional significance of receptor subtypes
17. Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem
18. Benzodiazepine receptors in rat brain
19. Involvement of GABAA receptor sites in diazepam hypothermia