Comparison of iron-catalyzed DNA and lipid oxidation

Journal of Biochemical and Molecular Toxicology

Volumn 15, Issue 2, 2001, Pages 114-119

  Djuric, Zora ^a   Potter, David W ^b   Taffe, Bonita G ^c   Strasburg, Gale M ^d  

^a KARMANOS CANCER INSTITUTE   (United States)

^b Rohme Haas Co   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Michigan State University   (United States)

Author keywords

Iron; Lipid peroxidation; Oxidative DNA damage; Oxidative stress

Indexed keywords

1 STEAROYL 2 LINOLEOYL SN GLYCERO 3 PHOSPHOCHOLINE; 4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; 5 HYDROXYMETHYLDEOXYURIDINE; 8 HYDROXYDEOXYGUANOSINE; BUFFER; CHOLINE DERIVATIVE; DNA; FERRIC ION; FERROUS ION; FLUORESCENT DYE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON; IRON CHELATE; LIPOSOME; PHOSPHATE; UNCLASSIFIED DRUG; URIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; INCUBATION TIME; LIPID OXIDATION; LIPID PEROXIDATION; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION; RAT;

ANIMALS; DEOXYGUANOSINE; DNA; FERRIC COMPOUNDS; FERROUS COMPOUNDS; FLUORESCENT DYES; HYDROGEN PEROXIDE; IRON; IRON CHELATING AGENTS; KINETICS; LIPID PEROXIDATION; LIPID PEROXIDES; LIPOSOMES; MICROSOMES, LIVER; OXIDATION-REDUCTION; RATS; RATS, WISTAR; THYMIDINE;

EID: 0035045337     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbt.7     Document Type: Article

References (25)

1. Measurement of lipid peroxidation
2. Antioxidant activities of isoflavones and their biological metabolites in a liposomal system
3. Development and validation of fluorescence spectroscopic assays to evaluate antioxidant efficacy: Application to metal chelators
4. New fluoresecent cholesterol analogs as membrane probes
5. A novel fluorescence assay to evaluate antioxidant efficacy: Application to flavonoids and isoflavonoids
6. Damage to the DNA bases in mammalian chromatin by hydrogen peroxide in the presence of ferric and cupric ions
7. Quantitation of 5-(hydroxymethyl)uracil in DNA by gas chromatographymass spectroscopy
8. Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo
9. 7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo
10. Microsomal electron transport
11. 3+, and oxygen react with DNA-derived radicals formed during iron-mediated Fenton reactions
12. The requirement for iron(III) in the initiation of lipid peroxidation by iron(II) and hydrogen peroxide
13. The role of iron in oxygen radical mediated lipid peroxidation
14. Comparison of 8-hydroxyguanine and 5-hydroxymethyluracil in oxidized DNA
15. Analysis of 5-hydroxy-2′-deoxycytidine and 5-hydroxymethyl-2′-deoxyuridine by GC/MS
16. The mechanism of initiation of lipid peroxidation: Evidence against a requirement for an iron(II)iron(III) complex
17. Fenton reagents may not initiate lipid peroxidation in an emulsified linoleic acid model system
18. Redox cycling of iron and lipid peroxidation
19. Iron(III) stimulated lipid hydroperoxide-dependent lipid peroxidation
20. Hydrogen peroxide-induced base damage in deoxyribonucleic acid
21. Mechanism of OH radical reactions with thymine and derivatives
22. The effect of different buffers on the oxidation of DNA by thiols and ferric ion
23. Inorganic phosphate promotes redox cycling of iron in liver micromosomes: Effects on free radical reactions
24. Hemoglobin: A mechanism for the generation of hydroxyl radicals
25. Conceptualization of the prooxidant and antioxidant actions of plant food chemicals